Commonly used drugs impair oral tolerance in mice

被引：8

作者：

Pecquet, S ^{[1
]}

Prioult, G ^{[1
]}

Campbell, J ^{[1
]}

German, B ^{[1
]}

Turini, M ^{[1
]}

机构：

[1] Nestle Res Ctr, CH-1000 Lausanne, Switzerland

来源：

ORAL TOLERANCE: NEW INSIGHTS AND PROSPECTS FOR CLINICAL APPLICATION | 2004年 / 1029卷

关键词：

oral tolerance; allergy; antibiotics; NSAIDs; weaning; food;

D O I：

10.1196/annals.1309.021

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ibuprofen and antibiotics are commonly prescribed during early childhood. When given to mice at the time at which oral tolerance is induced, both treatments affect either the induction or the maintenance of oral tolerance. These results suggest that the coadministration of these and similarly acting drugs should be considered cautiously for infants at risk of allergy.

引用

页码：374 / 378

页数：5

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