G-CSF and CD34+Progenitor Cells in Hematopoietic Grafts: Too Fertile for Human Cytomegalovirus

被引：0

作者：

Shimamura, Masako ^{[1
]}

Britt, William J. ^{[1
,2
,3
]}

机构：

[1] Univ Alabama, Sch Med, Dept Pediat, Childrens Hosp 160CHB, Birmingham, AL 35233 USA

[2] Univ Alabama, Sch Med, Dept Microbiol, Childrens Hosp 160CHB, Birmingham, AL 35233 USA

[3] Univ Alabama, Sch Med, Dept Neurobiol, Childrens Hosp 160CHB, Birmingham, AL 35233 USA

来源：

CELL HOST & MICROBE | 2010年 / 8卷 / 03期

关键词：

LATENT HUMAN CYTOMEGALOVIRUS; INFECTION;

D O I：

10.1016/j.chom.2010.08.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Smith et al. (2010) establish a humanized mouse model of latent host and cellular tropism of human cytomegalovirus (HCMV) infection and examine the effects of granulocyte-colony stimulating factor (GCSF) on human cytomegalovirus (HCMV) reactivation in vivo. HCMV-infected circulating CD34(+) myeloid cells populate end organs such as the liver and differentiate into cells capable of supporting lytic infection.

引用

页码：223 / 224

页数：2

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