Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation

被引：58

作者：

Soung, Do Y.

Dong, Yufeng

Wang, YongJun

Zuscik, Michael J.

Schwarz, Edward M.

O'Keefe, Regis J.

Drissi, Hicham ^{[1
]}

机构：

[1] Univ Rochester, Med Ctr, Dept Orthopaed, Rochester, NY 14642 USA

[2] Univ Rochester, Ctr Musculoskeletal Res, Rochester, NY USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 08期

关键词：

Runx3/Cbfa3; skeleton; chondrocytes; transfection;

D O I：

10.1359/JBMR.070502

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We studied the expression and function of Runx3 during chondrogenesis and chondrocyte maturation. We found that Runx3 is essential for mediating the early stage of endochondral ossification through cooperation with other Runx family members.

引用

页码：1260 / 1270

页数：11

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