Ternary complexes between DNA, polyamine, and cucurbituril: A modular approach to DNA-binding molecules

被引：0

作者：

Isobe, H

Tomita, N

Lee, JW

Kim, HJ

Kim, K

Nakamura, E ^{[1
]}

机构：

[1] Univ Tokyo, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

[2] Pohang Univ Sci & Technol, Dept Chem, Div Mol & Life Sci, POSTECH, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, POSTECH, Pohang 790784, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2000年 / 39卷 / 23期

关键词：

DNA recognition; Intercalation; Rotaxanes; Supramolecular chemistry;

D O I：

10.1002/1521-3773(20001201)39:23<4257::AID-ANIE4257>3.0.CO;2-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Attachment of small molecules to large biomolecules can occur through a supramolecular three-body modular-binding scheme (see scheme). This approach allows cucurbit[6]uril (C), which normally cannot bind to DNA, to be attached to double-stranded DNA (A) through a linker molecule (B) containing both an acridine moiety (which binds to DNA) and a spermine moiety (which binds cucurbit[6]uril).

引用

页码：4257 / +

页数：5

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