Gut Microbiota in Non-Alcoholic Fatty Liver Disease Patients with Inflammatory Bowel Diseases: A Complex Interplay

被引:25
|
作者
Abenavoli, Ludovico [1 ]
Giubilei, Lidia [1 ]
Procopio, Anna Caterina [1 ]
Spagnuolo, Rocco [1 ]
Luzza, Francesco [1 ]
Boccuto, Luigi [2 ]
Scarpellini, Emidio [3 ]
机构
[1] Magna Graecia Univ Catanzaro, Dept Hlth Sci, I-88100 Catanzaro, Italy
[2] Clemson Univ, Sch Nursing, Clemson, SC 29634 USA
[3] Katholieke Univ Leuven, Translat Res Gastrointestinal Disorders TARGID, Gasthuisberg Univ Hosp, Herestr 49, B-3000 Leuven, Belgium
关键词
microbiota; non-alcoholic fatty liver disease; Crohn's disease; ulcerative colitis; EXPRESSION; ABUNDANCE; DYSBIOSIS;
D O I
10.3390/nu14245323
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The intestinal microbiota represents the microbial community that colonizes the gastrointestinal tract and constitutes the most complex ecosystem present in nature. The main intestinal microbial phyla are Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucromicrobia, with a clear predominance of the two phyla Firmicutes and Bacteroidetes which account for about 90% of the intestinal phyla. Intestinal microbiota alteration, or dysbiosis, has been proven to be involved in the development of various syndromes, such as non-alcoholic fatty liver disease, Crohn's disease, and ulcerative colitis. The present review underlines the most recurrent changes in the intestinal microbiota of patients with NAFLD, Crohn's disease, and ulcerative colitis.
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页数:10
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