Redox tunable delivery systems: sweet block copolymer micelles via thiol-(bromo) maleimide conjugation

被引：15

作者：

Petrelli, Antoine ^{[1
]}

Borsali, Redouane ^{[1
]}

Fort, Sebastien ^{[1
]}

Halila, Sami ^{[1
]}

机构：

[1] Univ Grenoble Alpes, CNRS, CERMAV, F-38000 Grenoble, France

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 82期

关键词：

POLYMERIC MICELLES; NANOPARTICLES; THIOL; ENCAPSULATION; STABILITY;

D O I：

10.1039/c6cc07136h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Oligosaccharide-based block copolymers (OBCPs) are synthesized by thiol click conjugation using reducing-end thiol-containing xyloglucooligosaccharides and maleimide- or bromomaleimide-terminated polycaprolactone. The self-assembled OBCPs in aqueous solution lead to redox-sensitive micelles with different responsiveness. This distinguishing feature allows us to control the release of entrapped hydrophobic Nile red by mixing both OBCPs.

引用

页码：12202 / 12205

页数：4

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