Chronic Musculoskeletal Pain Moderates the Association between Sleep Quality and Dorsostriatal-Sensorimotor Resting State Functional Connectivity in Community-Dwelling Older Adults
被引:3
作者:
Montesino-Goicolea, Soamy
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机构:
Univ Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Univ Florida, Pain Res & Intervent Ctr Excellence, Gainesville, FL 32610 USA
Univ Florida, Evelyn F & William L McKnight Brain Inst, Gainesville, FL 32610 USAUniv Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Montesino-Goicolea, Soamy
[1
,2
,3
]
Valdes-Hernandez, Pedro A.
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h-index: 0
机构:
Univ Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Univ Florida, Pain Res & Intervent Ctr Excellence, Gainesville, FL 32610 USA
Univ Florida, Evelyn F & William L McKnight Brain Inst, Gainesville, FL 32610 USAUniv Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Valdes-Hernandez, Pedro A.
[1
,2
,3
]
Cruz-Almeida, Yenisel
论文数: 0引用数: 0
h-index: 0
机构:
Univ Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Univ Florida, Pain Res & Intervent Ctr Excellence, Gainesville, FL 32610 USA
Univ Florida, Evelyn F & William L McKnight Brain Inst, Gainesville, FL 32610 USA
Univ Florida, Inst Aging, Gainesville, FL 32610 USA
Univ Florida, Ctr Cognit Aging & Memory, Gainesville, FL 32610 USA
Univ Florida, Dept Neurosci, Coll Med, Gainesville, FL 32610 USAUniv Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
Cruz-Almeida, Yenisel
[1
,2
,3
,4
,5
,6
]
机构:
[1] Univ Florida, Dept Community Dent & Behav Sci, Gainesville, FL 32610 USA
[2] Univ Florida, Pain Res & Intervent Ctr Excellence, Gainesville, FL 32610 USA
[3] Univ Florida, Evelyn F & William L McKnight Brain Inst, Gainesville, FL 32610 USA
[4] Univ Florida, Inst Aging, Gainesville, FL 32610 USA
DIFFEOMORPHIC IMAGE REGISTRATION;
PRIMARY INSOMNIA;
CAUDATE-NUCLEUS;
HUMAN STRIATUM;
BASAL GANGLIA;
DEFAULT MODE;
MOTOR AREAS;
PREVALENCE;
NETWORKS;
AGE;
D O I:
10.1155/2022/4347759
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Aging is associated with poor sleep quality and greater chronic pain prevalence, with age-related changes in brain function as potential underlying mechanisms. Objective. The following cross-sectional study aimed to determine whether self-reported chronic musculoskeletal pain in community-dwelling older adults moderates the association between sleep quality and resting state functional brain connectivity (rsFC). Methods. Community-dwelling older individuals (mean age = 73.29 years) part of the NEPAL study who completed the Pittsburg Sleep Quality Index (PSQI) and a rsFC scan were included (n = 48) in the present investigation. To that end, we tested the effect of chronic pain-by-PSQI interaction on rsFC among atlas-based brain regions-of-interest, controlling for age and sex. Results and Discussion. A significant network connecting the bilateral putamen and left caudate with bilateral precentral gyrus, postcentral gyrus, and juxtapositional lobule cortex, survived global multiple comparisons (FDR; q < 0.05) and threshold-free network-based-statistics. Greater PSQI scores were significantly associated with greater dorsostriatal-sensorimotor rsFC in the no-pain group, suggesting that a state of somatomotor hyperarousal may be associated with poorer sleep quality in this group. However, in the pain group, greater PSQI scores were associated with less dorsostriatal-sensorimotor rsFC, possibly due to a shift of striatal functions toward regulation sensorimotor aspects of the pain experience, and/or aberrant cortico-striatal loops in the presence of chronic pain. This preliminary investigation advances knowledge about the neurobiology underlying the associations between chronic pain and sleep in community-dwelling older adults that may contribute to the development of effective therapies to decrease disability in geriatric populations.
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Xu, Hong-Zhou
Peng, Xue-Rui
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Tech Univ Dresden, Fac Psychol, Lifespan Dev Neurosci, Dresden, GermanySouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Peng, Xue-Rui
Liu, Yun-Rui
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Univ Basel, Fac Psychol, Ctr Cognit & Decis Sci, Basel, SwitzerlandSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Liu, Yun-Rui
Lei, Xu
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Lei, Xu
Yu, Jing
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Makino, Keitaro
Lee, Sangyoon
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Lee, Sangyoon
Lee, Sungchul
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Lee, Sungchul
Bae, Seongryu
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Japan Soc Promot Sci, Tokyo, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Bae, Seongryu
Jung, Songee
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Japan Soc Promot Sci, Tokyo, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Jung, Songee
Shinkai, Yohei
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Shinkai, Yohei
Shimada, Hiroyuki
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h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Griffioen, Mari A.
Bowen, Mary E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Corporal Michael J Crescenz VA Med Ctr, Philadelphia, PA USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Bowen, Mary E.
Resnick, Barbara
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Sch Nursing, Baltimore, MD 21201 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Resnick, Barbara
Renn, Cynthia L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Sch Nursing, Baltimore, MD 21201 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Renn, Cynthia L.
Ji, Xiaopeng
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Xu, Hong-Zhou
Peng, Xue-Rui
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Tech Univ Dresden, Fac Psychol, Lifespan Dev Neurosci, Dresden, GermanySouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Peng, Xue-Rui
Liu, Yun-Rui
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Univ Basel, Fac Psychol, Ctr Cognit & Decis Sci, Basel, SwitzerlandSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Liu, Yun-Rui
Lei, Xu
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Lei, Xu
Yu, Jing
论文数: 0引用数: 0
h-index: 0
机构:
Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R ChinaSouthwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Makino, Keitaro
Lee, Sangyoon
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Lee, Sangyoon
Lee, Sungchul
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Lee, Sungchul
Bae, Seongryu
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Japan Soc Promot Sci, Tokyo, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Bae, Seongryu
Jung, Songee
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Japan Soc Promot Sci, Tokyo, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Jung, Songee
Shinkai, Yohei
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Shinkai, Yohei
Shimada, Hiroyuki
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Prevent Gerontol, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Griffioen, Mari A.
Bowen, Mary E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Corporal Michael J Crescenz VA Med Ctr, Philadelphia, PA USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Bowen, Mary E.
Resnick, Barbara
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Sch Nursing, Baltimore, MD 21201 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Resnick, Barbara
Renn, Cynthia L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Sch Nursing, Baltimore, MD 21201 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA
Renn, Cynthia L.
Ji, Xiaopeng
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USAUniv Delaware, Sch Nursing, 100 Discovery Ave, Newark, DE 19713 USA