Biomaterials in the Treatment of Anal Fistula: Hope or Hype?

被引：19
作者：
Scoglio, Daniele [1 ]
Walker, Avery S. [2 ]
Fichera, Alessandro [1 ]
机构：
[1] Univ Washington, Med Ctr, Dept Surg, Seattle, WA 98195 USA
[2] Madigan Army Med Ctr, Dept Surg, Washington, DC USA
来源：
CLINICS IN COLON AND RECTAL SURGERY | 2014年 / 27卷 / 04期
关键词：
anal fistula; biologic mesh; fibrin glue; fistula plug; bio-LIFT; stem cells; ENDORECTAL ADVANCEMENT FLAP; SPHINCTER-SAVING TECHNIQUE; FIBRIN GLUE TREATMENT; TERM-FOLLOW-UP; IN-ANO; INTERSPHINCTERIC FISTULA; INITIAL-EXPERIENCE; SURGICAL-TREATMENT; PERIANAL FISTULAS; TRACT PROCEDURE;
D O I：
10.1055/s-0034-1394156
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Anal fistula (AF) presents a chronic problem for patients and colorectal surgeons alike. Surgical treatment may result in impairment of continence and long-term risk of recurrence. Treatment options for AFs vary according to their location and complexity. The ideal approach should result in low recurrence rates and minimal impact on continence. New technical approaches involving biologically derived products such as biological mesh, fibrin glue, fistula plug, and stem cells have been applied in the treatment of AF to improve outcomes and decrease recurrence rates and the risk of fecal incontinence. In this review, we will highlight the current evidence and describe our personal experience with these novel approaches.
引用
收藏
页码：172 / 181
页数：10
相关论文
共 93 条
  • [31] Elting AW, 1912, ANN SURG, V56, P744
  • [32] Expanded Adipose-Derived Stem Cells for the Treatment of Complex Perianal Fistula: a Phase II Clinical Trial
    Garcia-Olmo, Damian
    Herreros, Dolores
    Pascual, Isabel
    Antonio Pascual, Jose
    Del-Valle, Emilio
    Zorrilla, Jaime
    De-La-Quintana, Paloma
    Garcia-Arranz, Mariano
    Pascual, Maria
    [J]. DISEASES OF THE COLON & RECTUM, 2009, 52 (01) : 79 - 86
  • [33] The efficacy of anal fistula plug in fistula-in-ano: a systematic review
    Garg, P.
    Song, J.
    Bhatia, A.
    Kalia, H.
    Menon, G. R.
    [J]. COLORECTAL DISEASE, 2010, 12 (10) : 965 - 970
  • [34] Treatment of fistulas in ano with fibrin glue
    Gisbertz, SS
    Sosef, MN
    Festen, S
    Gerhards, MF
    [J]. DIGESTIVE SURGERY, 2005, 22 (1-2) : 91 - 94
  • [35] Endorectal Mucosal Advancement Flap: The Preferred Method for Complex Cryptoglandular Fistula-in-Ano
    Golub R.W.
    Wise Jr. W.E.
    Kerner B.A.
    Khanduja K.S.
    Aguilar P.S.
    [J]. Journal of Gastrointestinal Surgery, 1997, 1 (5) : 487 - 491
  • [36] Long-term follow-up of patients undergoing adipose-derived adult stem cell administration to treat complex perianal fistulas
    Guadalajara, Hector
    Herreros, Dolores
    De-La-Quintana, Paloma
    Trebol, Jacobo
    Garcia-Arranz, Mariano
    Garcia-Olmo, Damian
    [J]. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2012, 27 (05) : 595 - 600
  • [37] Who Is At Risk for Developing Chronic Anal Fistula or Recurrent Anal Sepsis After Initial Perianal Abscess?
    Hamadani, Ali
    Haigh, Philip I.
    Liu, In-Lu A.
    Abbas, Maher A.
    [J]. DISEASES OF THE COLON & RECTUM, 2009, 52 (02) : 217 - 221
  • [38] Novel biomaterials in the management of anal fistulas
    Hammond, T. M.
    Lunniss, P. J.
    [J]. DISEASES OF THE COLON & RECTUM, 2006, 49 (09) : 1463 - 1464
  • [39] Hammond T M, 2004, Colorectal Dis, V6, P308, DOI 10.1111/j.1463-1318.2004.00676.x
  • [40] Ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug (LIFT-Plug): a new technique for fistula-in-ano
    Han, J. G.
    Yi, B. Q.
    Wang, Z. J.
    Zheng, Y.
    Cui, J. J.
    Yu, X. Q.
    Zhao, B. C.
    Yang, X. Q.
    [J]. COLORECTAL DISEASE, 2013, 15 (05) : 582 - 586
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