Lewis acid-catalyzed 2-arylquinazoline formation from N′-arylbenzimidamides and paraformaldehyde

被引：49
作者：
Cheng, Xiufang [1 ]
Wang, Huamin [1 ]
Xiao, Fuhong [1 ]
Deng, Guo-Jun [1 ]
机构：
[1] Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environm Friendly Chem & Applicat, Xiangtan 411105, Peoples R China
来源：
GREEN CHEMISTRY | 2016年 / 18卷 / 21期
基金：
中国国家自然科学基金;
关键词：
2-SUBSTITUTED QUINAZOLINES; MULTICOMPONENT REACTIONS; ACRIDONE ALKALOIDS; DERIVATIVES; CYCLIZATION; INHIBITORS; ALDEHYDES; BENZAMIDINES; FORMALDEHYDE; ANNULATION;
D O I：
10.1039/c6gc02319c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient procedure for the synthesis of 2-arylquinazolines from N'-arylbenzimidamides has been developed under transitionmetal-free conditions. In this process, stable and low-toxicity paraformaldehyde was used as the carbon source. A broad range of functional groups were well tolerated in this reaction system.
引用
收藏
页码：5773 / 5776
页数：4
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