The novel YAP1 activator induces YAP1-p73 pathway-dependent apoptosis in human multiple myeloma cells

被引：0
|
作者：
Maruyama, Junichi [1 ]
Kagechika, Hiroyuki [2 ]
Nishina, Hiroshi [3 ]
Hata, Yutaka [1 ]
机构：
[1] TMDU, Grad Sch Med Dent Sci, Med Biochem, Tokyo, Japan
[2] TMDU, Inst Biomat Bioengn, Org Med Chem, Tokyo, Japan
[3] TMDU, Med Res Inst, Devel Regen Biol, Tokyo, Japan
来源：
CANCER SCIENCE | 2018年 / 109卷
关键词：
Multiple myeloma; Screening;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P-1078
引用
收藏
页码：204 / 204
页数：1
相关论文
共 50 条
  • [21] Endothelin-1 (ET-1) induces resistance to bortezomib in human multiple myeloma cells via a pathway involving the ETB receptor and upregulation of proteasomal activity
    Maria Vaiou
    Evanthia Pangou
    Panagiotis Liakos
    Nikos Sakellaridis
    George Vassilopoulos
    Konstantinos Dimas
    Christos Papandreou
    Journal of Cancer Research and Clinical Oncology, 2016, 142 : 2141 - 2158
  • [22] Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription
    Manohar, Sonal M.
    Rathos, Maggie J.
    Sonawane, Vinay
    Rao, Shalini V.
    Joshi, Kalpana S.
    LEUKEMIA RESEARCH, 2011, 35 (06) : 821 - 830
  • [23] Histone deacetylase inhibitor LMK-235-mediated HO-1 expression induces apoptosis in multiple myeloma cells via the JNK/AP-1 signaling pathway
    Li, Xinyao
    Guo, Yongling
    Kuang, Xingyi
    Zhao, Lu
    Li, Hongsong
    Cheng, Bingqing
    Wang, Weili
    Zhang, Zhaoyuan
    Liu, Ping
    Wang, Jishi
    LIFE SCIENCES, 2019, 223 : 146 - 157
  • [24] NUPR1 Silencing Induces Autophagy-Mediated Apoptosis in Multiple Myeloma Cells Through the PI3K/AKT/mTOR Pathway
    Li, Anmao
    Li, Xingxin
    Chen, Xuanxin
    Zeng, Chensi
    Wang, Zuo
    Li, Zhen
    Chen, Jianbin
    DNA AND CELL BIOLOGY, 2020, 39 (03) : 368 - 378
  • [25] Overexpression of microRNA-29b induces apoptosis of multiple myeloma cells through down regulating Mcl-1
    Zhang, Yi-Kun
    Wang, Hua
    Leng, Yun
    Li, Ze-Liang
    Yang, Yue-Feng
    Xiao, Feng-Jun
    Li, Qing-Fang
    Chen, Xie-Qun
    Wang, Li-Sheng
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 414 (01) : 233 - 239
  • [26] Arylazopyrazole AAP1742 Inhibits CDKs and Induces Apoptosis in Multiple Myeloma Cells via Mcl-1 Downregulation
    Jorda, Radek
    Navratilova, Jana
    Huskova, Zlata
    Schuetznerova, Eva
    Cankar, Petr
    Strnad, Miroslav
    Krystof, Vladimir
    CHEMICAL BIOLOGY & DRUG DESIGN, 2014, 84 (04) : 402 - 408
  • [27] Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: Possible anti-myeloma mechanism of thalidomide
    Iguchi, Toyotaka
    Yachide-Noguch, Tomomi
    Hashimoto, Yuichi
    Nakazato, Sawako
    Sagawa, Morihiko
    Ikeda, Yasuo
    Kizaki, Masahiro
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2008, 21 (02) : 163 - 168
  • [28] AP-1 inhibitor induces ferroptosis via the PI3K/AKT pathway in multiple myeloma cells
    Tang, Sishi
    Liu, Jing
    Li, Fangfang
    Yan, Yuhan
    Long, Xinyi
    Fu, Yunfeng
    HELIYON, 2024, 10 (14)
  • [29] Benzimidazole derivative, BMT-1, induces apoptosis in multiple myeloma cells via a mitochondrial-mediated pathway involving H+/K+-ATPase inhibition
    Yang, Tai
    Li, Min-Hui
    Liu, Jin
    Huang, Ning
    Li, Ning
    Liu, Si-Nian
    Liu, Yang
    Zhang, Tao
    Zou, Qiang
    Li, Hua
    ONCOLOGY REPORTS, 2014, 31 (06) : 2743 - 2750
  • [30] SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling
    Xu, Jun
    Sun, Hui-Yan
    Xiao, Feng-Jun
    Wang, Hua
    Yang, Yang
    Wang, Lu
    Gao, Chun-Ji
    Guo, Zi-Kuan
    Wu, Chu-Tse
    Wang, Li-Sheng
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 460 (02) : 409 - 415
12345