Subcutaneous Sweet Syndrome Successfully Treated With Ustekinumab in a Patient With Ulcerative Colitis

被引:4
作者
Hu, Kelly A. A. [1 ]
Shen, Jeanne [2 ]
Rieger, Kerri [3 ]
Wei, Mike T. T. [1 ,4 ]
Gubatan, John [1 ,4 ]
机构
[1] Stanford Univ, Sch Med, Dept Med, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Pathol, Sch Med, Stanford, CA USA
[3] Stanford Univ, Sch Med, Dept Dermatol, Stanford, CA USA
[4] Stanford Univ, Sch Med, Div Gastroenterol & Hepatol, Stanford, CA 94305 USA
关键词
INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; EXTRAINTESTINAL MANIFESTATIONS; MAINTENANCE THERAPY; INDUCTION;
D O I
10.14309/crj.0000000000000881
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Ustekinumab, an inhibitor of the interleukin-12/23 pathway, received Food and Drug Administration (FDA) approval in 2019 for induction and maintenance therapy in patients with moderate-to-severe ulcerative colitis (UC). Data regarding the efficacy of ustekinumab in the treatment of extraintestinal manifestations of UC are unclear. Sweet syndrome, an acute febrile neutrophilic dermatosis, is a cutaneous manifestation of inflammatory bowel disease that parallels disease activity. In this study, we present the first case of subcutaneous Sweet syndrome with sterile osteomyelitis in a patient with UC successfully treated with ustekinumab.
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页数:4
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