To address increasingly urgent global environmental challenges, there is a need for rapid and widespread adoption of eco-innovations. Previous research has shown that targeting key initial adopters using network-based strategies is an effective way to increase the adoption and diffusion of innovations; however, these models have not specifically been applied to the diffusion of eco-innovations through inter-firm networks. Therefore, this paper develops an agent-based model that tests various network-based targeting strategies on generated interfirm networks with different parameters to understand mechanisms that could boost and accelerate the adoption and diffusion of eco-innovations. The results show that targeting firms with high degree or high influence could more quickly diffuse incremental eco-innovations, while targeting neighbors of adopters is a better strategy for more radical eco-innovations with greater barriers to adoption. This has implications for policymakers, companies, and startups who wish to accelerate eco-innovation adoption and diffusion to create positive societal impacts.