A clean one-pot synthesis of 7-amino-5-aryl-6-cyano-1,5-dihydro-2H-pyrano[2,3-d] pyrimidine-2,4(3H)-diones in aqueous media under ultrasonic irradiation

被引：0

作者：

Jin, TS ^{[1
]}

Liu, LB ^{[1
]}

Zhao, Y ^{[1
]}

Li, TS ^{[1
]}

机构：

[1] Hebei Univ, Coll Chem & Environm Sci, Baoding 071002, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2005年 / 03期

关键词：

barbituric acid; dione; heterocyclic compounds; aqueous media;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel approach to the synthesis of 7-amino-5-aryl-6-cyano-1,5-dihydro-2H-pyrano[2,3-d]pyrimidine-2,4(3H)-diones in aqueous media under ultrasonic irradiation without catalyst is described. This method provides several advantages such as being environmentally friendly, simple work-up procedure and milder condition. In addition, water was chosen as a green solvent.

引用

页码：162 / 163

页数：2

共 16 条

[1] Anastas P. T., 1998, GREEN CHEM FRONTIERS
[2] Cornils B., 2006, Aqueous -Phase Organometallic Catalysis: Concepts and Applications
[3] Effective synthesis of 7-amino-6-cyano-5-aryl-5H-pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones under microwave irradiation
Gao, Y
Tu, SJ
Li, TJ
Zhang, XJ
Zhu, SL
Fang, F
Shi, DQ
[J]. SYNTHETIC COMMUNICATIONS, 2004, 34 (07) : 1295 - 1299
[4] Grieco P.A., 1998, Organic synthesis in water
[5] Design constraints in practical syntheses of complex molecules: Current status, case studies with carbohydrates and alkaloids, and future perspectives
Hudlicky, T
[J]. CHEMICAL REVIEWS, 1996, 96 (01) : 3 - 30
[6] IBRAHIM MKA, 1987, INDIAN J CHEM B, V26, P216
[7] Ultrasound-assisted synthesis of 2-amino-2-chromenes with cetyltrimethylammonium bromide in aqueous media
Jin, TS
Xiao, JC
Wang, SJ
Li, TS
[J]. ULTRASONICS SONOCHEMISTRY, 2004, 11 (06) : 393 - 397
[8] Li C. -J., 1997, ORGANIC REACTIONS AQ
[9] Luche J. L, 1998, SYNTHETIC ORGANIC SO
[10] Mason T.J., 2002, Practical Sonochemistry: Uses and Applications of Ultrasound

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