Cyclic AMP phosphodiesterase inhibitory activity and chemical screening of four medicinal plants

被引：14

作者：

Chit, K

Myint, W

Thein, K

Maw, WW

Myint, MM

Than, A

Khin, M

机构：

[1] Dept Med Res, Pharmacol Res Div, Yangon, Myanmar

[2] Dept Med Res, Nucl Med Res Div, Yangon, Myanmar

来源：

PHARMACEUTICAL BIOLOGY | 2001年 / 39卷 / 03期

关键词：

phosphodiesterase inhibition; chemical screening; Acorus calamus Linn; Alpinia galanga Willd; Desmodium triquetrum DC and Vitis discolour Dalz;

D O I：

10.1076/phbi.39.3.181.5932

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four medicinal plants, Acorus calamus Linn., Alpinia galanga Willd., Desmodium triquetrum D.C. and Vitis discolour Dalz., were investigated for potential to inhibit cyclic AMP phosphodiesterase. The alcohol extract of Desmodium triquetrum was found to be most active. The chloroform and alcohol extracts of Desmodium triquetrum and Acorus calamus, and the petroleum ether and chloroform extracts of Alpinia galanga contain flavonoids. These are possibly the active principles responsible for their anti-bacterial activity.

引用

页码：181 / 183

页数：3

共 16 条

[1]

*AGR CORP, 1980, BURM MED PLANTS, P411

[2]

BAKER CA, 1965, FLORA JAVA, P604

[3] ASSAY OF ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE AND GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE IN BIOLOGICAL MATERIALS BY ENZYMATIC RADIOISOTOPIC DISPLACEMENT [J].