Positron emission tomography molecular imaging-based cancer phenotyping

被引：21

作者：

Jin, Chentao ^{[1
,2
,3
,4
]}

Luo, Xiaoyun ^{[1
,2
,3
,4
]}

Li, Xiaoyi ^{[1
,2
,3
,4
]}

Zhou, Rui ^{[1
,2
,3
,4
]}

Zhong, Yan ^{[1
,2
,3
,4
]}

Xu, Zhoujiao ^{[1
,2
,3
,4
]}

Cui, Chunyi ^{[1
,2
,3
,4
]}

Xing, Xiaoqing ^{[1
,2
,3
,4
]}

Zhang, Hong ^{[1
,2
,3
,4
,5
,6
]}

Tian, Mei ^{[1
,2
,3
,4
]}

机构：

[1] Zhejiang Univ, Dept Nucl Med, Affiliated Hosp 2, Sch Med, Hangzhou, Peoples R China

[2] Zhejiang Univ, Positron Emiss Tomog Ctr, Affiliated Hosp 2, Sch Med, Hangzhou, Peoples R China

[3] Zhejiang Univ, Inst Nucl Med & Mol Imaging, Hangzhou, Peoples R China

[4] Key Lab Med Mol Imaging Zhejiang Prov, Hangzhou, Peoples R China

[5] Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Hangzhou, Peoples R China

[6] Zhejiang Univ, Key Lab Biomed Engn, Minist Educ, Hangzhou, Peoples R China

来源：

CANCER | 2022年 / 128卷 / 14期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

biomarker; cancer; cancer hallmarks; molecular imaging; positron emission tomography (PET); translational medicine; TUMOR-ASSOCIATED MACROPHAGES; PROSTATE-CANCER; BREAST-CANCER; AMINO-ACIDS; PET; EXPRESSION; VISUALIZATION; REPORTER; RECEPTOR; INFLAMMATION;

D O I：

10.1002/cncr.34228

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

During the past several decades, numerous studies have provided insights into biological characteristics of cancer cells and identified various hallmarks of cancer acquired in the tumorigenic processes. However, it is still challenging to image these distinctive traits of cancer to facilitate the management of patients in clinical settings. The rapidly evolving field of positron emission tomography (PET) imaging has provided opportunities to investigate cancer's biological characteristics in vivo. This article reviews the current status of PET imaging on characterizing hallmarks of cancer and discusses the future directions of PET imaging strategies facilitating in vivo cancer phenotyping.

引用

页码：2704 / 2716

页数：13

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