Catalytic Fehling's Reaction: An Efficient Aerobic Oxidation of Aldehyde Catalyzed by Copper in Water

被引：90
|
作者：
Liu, Mingxin [1 ,2 ]
Li, Chao-Jun [1 ,2 ]
机构：
[1] McGill Univ, Dept Chem, Montreal, PQ H3A 0B8, Canada
[2] McGill Univ, FRQNT Ctr Green Chem & Catalysis, Montreal, PQ H3A 0B8, Canada
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2016年 / 55卷 / 36期
关键词：
copper; homogeneous catalysis; oxidation; reaction mechanisms; ACETYLACETONATE COMPLEXES; MOLECULAR-OXYGEN; CARBOXYLIC-ACIDS; ALCOHOLS; NHC;
D O I：
10.1002/anie.201604847
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first example of homogeneous copper-catalyzed aerobic oxidation of aldehydes is reported. This method utilizes atmospheric oxygen as the sole oxidant, proceeds under extremely mild aqueous conditions, and covers a wide range of various functionalized aldehydes. Chromatography is generally not necessary for product purification.
引用
收藏
页码：10806 / 10810
页数：5
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