Research Progress on Natural Benzophenanthridine Alkaloids and their Pharmacological Functions: A Review

被引：0
|
作者：
Han, Na [1 ]
Yang, Zhiyou [1 ]
Liu, Zhihui [1 ]
Liu, Huijing [1 ]
Yin, Jun [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Dev & Utilizat Key Lab Northeast Plant Mat, Shenyang 110016, Peoples R China
来源：
NATURAL PRODUCT COMMUNICATIONS | 2016年 / 11卷 / 08期
关键词：
Benzophenanthridine alkaloids; Biosynthesis; Distribution; Biotransformation; Metabolism; Spectral characteristics; Pharmacological activities; Toxicity; AMBIGUA VAR. AMURENSIS; CHELIDONIUM-MAJUS; ZANTHOXYLUM-NITIDUM; STEM BARK; CORYDALIS-INCISA; FREE BASES; ROOT BARK; PAPAVERACEAE; QUATERNARY; INTEGRIFOLIOLUM;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Benzophenanthridine alkaloids belong to the benzyl isoquinoline family of alkaloids, which are mainly found in Papaveraceae and Rutaceae. To date, over 100 compounds have been isolated from natural herbal medicines which display a variety of pharmacological functions. In this paper, we have summarized the work since 1980 and our own research on benzophenanthridine alkaloids in terms of their chemical structures and distribution, biosynthesis, biotransformation and metabolism, spectral characteristics, pharmacological activities and toxicity. This review lays the foundation for further research into benzophenanthridine alkaloids and their potential applications.
引用
收藏
页码：1181 / 1188
页数：8
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