New hybrids between triterpenoid acids and nucleoside HIV-RT inhibitors

被引：10

作者：

Anh Thi Tuyet Dang ^{[1
]}

Chinh The Pham ^{[1
]}

Than Anh Le ^{[2
]}

Hieu Hong Truong ^{[1
]}

Ha Thu Thi Vu ^{[1
]}

Soldatenkov, Anatoly T. ^{[3
]}

Tuyen Van Nguyen ^{[1
]}

机构：

[1] Vietnam Acad Sci & Technol, Inst Chem, Hanoi, Vietnam

[2] VNU Univ Sci, Fac Chem, Hanoi, Vietnam

[3] Peoples Friendship Univ Russia, Dept Chem, Moscow 117198, Russia

来源：

MENDELEEV COMMUNICATIONS | 2015年 / 25卷 / 02期

关键词：

REVERSE-TRANSCRIPTASE INHIBITOR; ANTI-AIDS AGENTS; BETULINIC ACID; BIOLOGICAL EVALUATION; PROTEASE INHIBITORS; DOUBLE-DRUGS; DERIVATIVES; LINKER; AZT;

D O I：

10.1016/j.mencom.2015.03.004

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

One-pot synthesis of ester-linked conjugates of betulinic, ursolic or oleanolic acids with anti-HIV drugs AZT, derivatives of AZT and 3TC was performed, the resulting conjugates having shown high anti-HIV activities.

引用

页码：96 / 98

页数：3

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