Prenatal Maternal Stress and the Risk of Lifetime Wheeze in Young Offspring: An Examination by Stressor and Maternal Ethnicity

被引：18

作者：

Bandoli, Gretchen ^{[1
]}

von Ehrenstein, Ondine ^{[2
]}

Ghosh, Jo Kay C.

Flores, Marie E. S. ^{[3
]}

Schetter, Christine Dunkel ^{[4
]}

Ritz, Beate ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Epidemiol, Box 951772, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Community Hlth Sci, Fielding Sch Publ Hlth, Los Angeles, CA USA

[3] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Family & Social Med, Univ Hosp, Bronx, NY 10467 USA

[4] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA USA

来源：

JOURNAL OF IMMIGRANT AND MINORITY HEALTH | 2016年 / 18卷 / 05期

关键词：

Prenatal stress; Childhood wheeze; Latina ethnicity; Fetal programming; 1ST; 6; YEARS; PRETERM BIRTH; LOS-ANGELES; ASTHMA; PREGNANCY; CHILDREN; CALIFORNIA; CHILDHOOD; OUTCOMES; MOTHERS;

D O I：

10.1007/s10903-015-0269-y

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Prenatal psychosocial stressors may increase the risk of wheeze in young offspring, yet little attention has been given to the effects that maternal ethnicity may have on this relationship. From a population-based cohort of 1193 children, we assessed the effect of maternal prenatal stressors on the risk of lifetime wheeze in young offspring. We further studied whether maternal Latina ethnicity modified these associations. The risk of wheeze in the offspring was increased from high levels of pregnancy anxiety (aRR 1.40, 95 % CI 1.07, 1.83), negative life events (aRR 1.36, 95 % CI 1.06, 1.75), or low paternal support (aRR 1.41, 95 % CI 1.02, 1.96). The risk of lifetime wheeze was stronger in the offspring of Latina mothers than of White mothers for these same stressors. Multiple maternal prenatal stressors are associated with increased risk of lifetime wheeze in young offspring, with slight effect modification by Latina ethnicity.

引用

页码：987 / 995

页数：9

共 34 条

[1] INTERNATIONAL STUDY OF ASTHMA AND ALLERGIES IN CHILDHOOD (ISAAC) - RATIONALE AND METHODS [J].