Sjogren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine

被引：8

作者：

Kelly, Anzola Luz ^{[1
,2
,3
]}

Nelson, Rivera Jose ^{[4
]}

Sara, Ramirez ^{[3
]}

Alberto, Signore ^{[5
]}

机构：

[1] Clin Univ Colombia, Nucl Med Unit, Bogota 111321, Colombia

[2] Nucl Med Unit, Clin Reina Sofia, Bogota 110121, Colombia

[3] Fdn Univ Sanitas, Bogota 110111, Colombia

[4] Clin Reina Sofia, Internal Med Dept, Bogota 110121, Colombia

[5] Sapienza Univ, Fac Med & Psychol, Dept Med Surg Sci & Translat Med, Nucl Med Unit, I-00185 Rome, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2022年 / 11卷 / 17期

关键词：

Sjogren syndrome; nuclear medicine; radiopharmaceuticals; PET; SPECT; LYMPHOID-LIKE STRUCTURES; SALIVARY-GLANDS; RHEUMATOID-ARTHRITIS; EPITHELIAL-CELLS; DISEASE-ACTIVITY; AUTOIMMUNE; RISK; SOMATOSTATIN; LYMPHOCYTES; ACTIVATION;

D O I：

10.3390/jcm11175227

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnostic and therapeutic approaches. In this review, we focus on the new pathophysiological findings for Sjogren syndrome and on the derived new SPECT and PET radiopharmaceuticals to detect inflammation of immunological origin, focusing on their role in diagnosis, prognosis, and the evaluation of therapeutic efficacy.

引用

页数：16

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