Candle soot derived carbon nanoparticles: Assessment of physico-chemical properties, cytotoxicity and genotoxicity

被引:24
作者
Singh, Shiv [1 ]
Singh, Divya [1 ]
Singh, Sheelendra Pratap [2 ,3 ]
Pandey, Alok Kumar [1 ]
机构
[1] IITR, CSIR, Nanomat Toxicol Grp, Vishvigyan Bhawan,31 Mahatma Gandhi Marg, Lucknow 226001, Uttar Pradesh, India
[2] Regulatory Toxicol Grp, Analyt Chem Lab, Pesticide Toxicol Lab, Vishvigyan Bhawan,31 Mahatma Gandhi Marg, Lucknow 226001, Uttar Pradesh, India
[3] IITR, CSIR, Vishvigyan Bhawan,31 Mahatma Gandhi Marg, Lucknow 226001, Uttar Pradesh, India
关键词
Carbon nanoparticles; Candle soot; Cytotoxicity; Reactive oxygen species assay; Genotoxicity; MICRO-NANOFIBERS; DOTS; EFFICIENT; ELECTRODE; NITROGEN; CELL;
D O I
10.1016/j.chemosphere.2018.09.112
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In this study, an evaluation of physico-chemical properties, cytotoxicity and genotoxicity of candle soot derived carbon nanoparticles (CNPs) was carried out. Several physico-chemical characterizations including scanning electron microscopy, transmission electron microscope, Brunauer-Emmet-Teller surface area and pore-size distribution, X-ray diffraction, Fourier transform infrared and Raman spectroscopy were implemented to characterize prepared CNPs. Propidium iodide uptake, reactive oxygen species assay and trypan blue exclusion and comet assay tests were executed to determine the toxicity of CNPs. It is found that the CNPs have insignificant cytotoxicity and genotoxicity and could be used in diverse biological and environmental applications as an alternative to expensive less toxic carbon materials. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:130 / 135
页数:6
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