The effect of loading rate and degeneration on neutral region motion in human cadaveric lumbar motion segments

被引:27
作者
Gay, Ralph E. [1 ,2 ]
Ilharreborde, Brice [2 ]
Zhao, Kristin [2 ]
Bournediene, Emir [2 ]
An, Kai-Nan [2 ]
机构
[1] Mayo Clin, Dept Phys Med & Rehabil, Rochester, MN 55905 USA
[2] Mayo Clin, Biomech Lab, Div Orthoped Res, Rochester, MN 55905 USA
关键词
neutral zone; lumbar vertebrae; intervertebral disc degeneration; methods; biomechanics;
D O I
10.1016/j.clinbiomech.2007.08.006
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Background The quasistatic neutral zone is a surrogate for neutral region stiffness of spinal motion segments. No similar measure of dynamic stiffness has been validated. Because parameters related to stiffness are likely to be affected by loading rate and disc degeneration, we examined the effect of those factors on motion parameters derived from continuous motion data. Methods. Fifteen human lumbar motion segments were tested with continuous flexion-extension pure moments at 0.5, 3.0 and 6.0 degrees/s. Range of motion, width of the hysteresis loop, transitional zone width, and slopes of the upper and lower arms of the hysteresis loop within the transitional zone were measured. Discs were then graded for degeneration. Findings. As the loading rate increased from 0.5 degrees/s to 6.0 degrees/s there were significant increases in range of motion, hysteresis area, hysteresis loop width, and the upper and lower transitional zone slopes. At the same time transitional zone width decreased significantly. Degeneration had a significant effect on all parameters except hysteresis loop width. The transition zone slopes appeared to best discriminate between normal and degenerative discs. Interpretation. Loading rate had a significant effect on all parameters. As degeneration increased consistent effects were observed indicating decreasing stiffness from grade 1 to grade 3 then slightly increased stiffness in grade 4 specimens. The slopes of the transitional zone have potential to be a useful measure of neutral region stiffness during dynamic motion testing. (C) 2007 Elsevier Ltd. All rights reserved.
引用
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页码:1 / 7
页数:7
相关论文
共 30 条
[1]   'Stress' distributions inside intervertebral discs - The effects of age and degeneration [J].
Adams, MA ;
McNally, DS ;
Dolan, P .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1996, 78B (06) :965-972
[2]   DIURNAL-VARIATIONS IN THE STRESSES ON THE LUMBAR SPINE [J].
ADAMS, MA ;
DOLAN, P ;
HUTTON, WC .
SPINE, 1987, 12 (02) :130-137
[3]   The Saskatchewan health and back pain survey -: The prevalence of low back pain and related disability in Saskatchewan adults [J].
Cassidy, JD ;
Carroll, LJ ;
Côté, P .
SPINE, 1998, 23 (17) :1860-1866
[4]  
Crawford NR, 1998, J SPINAL DISORD, V11, P416
[5]   Noise reduction in spine videofluoroscopic images using the undecimated wavelet transform [J].
De Stefano, A ;
Allen, R ;
White, PR .
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, 2004, 28 (08) :453-459
[6]   VARIATION OF LUMBAR SPINE STIFFNESS WITH LOAD [J].
EDWARDS, WT ;
HAYES, WC ;
POSNER, I ;
WHITE, AA ;
MANN, RW .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1987, 109 (01) :35-41
[7]   The relationship between disc degeneration, facet joint osteoarthritis, and stability of the degenerative lumbar spine [J].
Fujiwara, A ;
Tamai, K ;
An, HS ;
Kurihashi, A ;
Lim, TH ;
Yoshida, H ;
Saotome, K .
JOURNAL OF SPINAL DISORDERS, 2000, 13 (05) :444-450
[8]   Sagittal plane motion in the human lumbar spine: Comparison of the in vitro quasistatic neutral zone and dynamic motion parameters [J].
Gay, Ralph E. ;
Ilharreborde, Brice ;
Zhao, Kristin ;
Zhao, Chunfeng ;
An, Kai-Nan .
CLINICAL BIOMECHANICS, 2006, 21 (09) :914-919
[9]   Neutral zone and range of motion in the spine are greater with stepwise loading than with a continuous loading protocol. An in vitro porcine investigation [J].
Goertzen, DJ ;
Lane, C ;
Oxland, TR .
JOURNAL OF BIOMECHANICS, 2004, 37 (02) :257-261
[10]   Cineradiographic motion analysis of normal lumbar spine during forward and backward flexion [J].
Harada, M ;
Abumi, K ;
Ito, M ;
Kaneda, K .
SPINE, 2000, 25 (15) :1932-1937