Current Approaches in Improving Hemocompatibility of Polymeric Membranes for Biomedical Application

被引：41

作者：

Salimi, Esmaeil ^{[1
,2
]}

Ghaee, Azadeh ^{[1
]}

Ismail, Ahmad Fauzi ^{[2
]}

Othman, Mohd Hafiz Dzarfan ^{[2
]}

Sean, Goh Pei ^{[2
]}

机构：

[1] Univ Tehran, Dept Life Sci Engn, Fac New Sci & Technol, POB 143951374, Tehran 1439957131, Iran

[2] Univ Teknol Malaysia, Adv Membrane Technol Res Ctr AMTEC, Skudai 81310, Johor, Malaysia

来源：

MACROMOLECULAR MATERIALS AND ENGINEERING | 2016年 / 301卷 / 07期

关键词：

biocompatibility; blood compatibility tests; blood contacting membrane; chemical modifications; TRANSFER RADICAL POLYMERIZATION; HOLLOW-FIBER MEMBRANE; POLYETHERSULFONE ULTRAFILTRATION MEMBRANES; THERMOPLASTIC POLYURETHANE MEMBRANE; POLY(ETHYLENE GLYCOL) METHACRYLATE; GRAFTING SULFOBETAINE MONOMER; PROTEIN-ADSORPTION-RESISTANCE; PLASMA-INDUCED POLYMERIZATION; IMPROVED BLOOD COMPATIBILITY; IN-VITRO HEMOCOMPATIBILITY;

D O I：

10.1002/mame.201600014

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Suitable membranes for blood-contacting medical applications need to be resistant in confrontation with blood proteins and cells, while possessing high blood compatibility and permeability at the same time. Herein, an overview of the recent advances and strategies that have been used to enhance the hemocompatibility of polymeric membranes is provided. The review focuses on two modification strategies: (i) physical modifications and (ii) chemical modifications. It also highlights the current progress in the design of hemocompatible-functionalized membranes for biomedical applications. Subsequently, the commonly applied biocompatibility tests are also discussed and finally the future perspectives of the application of polymeric membranes in the biomedical field are presented.

引用

页码：771 / 800

页数：30

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