Incidental findings in brain imaging research: spotlight on ethical considerations

被引：4

作者：

Bhaskar, Sonu M. M. ^{[1
,2
,3
,4
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机构：

[1] Ingham Inst Appl Med Res Sydney, Clin Sci Stream, Sydney & Neurovasc Imaging Lab, Global Hlth Neurol & Translat Neurosci Lab, Sydney, NSW, Australia

[2] NSW Hlth Pathol, NSW Brain Clot Bank, Sydney, NSW, Australia

[3] Liverpool Hosp, Liverpool Hosp & South Western Sydney Local Hlth, Dept Neurol & Neurophysiol, Comprehens Stroke Ctr, Clinical Sci Bldg,Elizabeth St, Liverpool, NSW 2170, Australia

[4] Ingham Inst Appl Med Res, Stroke & Neurol Res Grp, Sydney, NSW, Australia

来源：

EUROPEAN RADIOLOGY | 2022年 / 32卷 / 10期

关键词：

Neuroimaging; Incidental findings; Neuroscience; Ethics; Health equity;

D O I：

10.1007/s00330-022-08944-8

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Brain imaging has revolutionized our ability to characterize brain structure and function. Since the first use of magnetic resonance imaging in a live human subject in 1977, the use of brain imaging in research and clinical medicine has seen exponential growth. Incidental findings (IFs) in brain imaging research have been a subject of contentious debate regarding the disclosure of IFs to human participants of research. In this paper, ethical considerations, as they apply, to IFs in brain imaging research have been discussed.

引用

页码：6977 / 6978

页数：2

共 10 条

[1] PERSPECTIVES OF CANADIAN RESEARCHERS ON ETHICS REVIEW OF NEUROIMAGING RESEARCH [J].

Deslauriers, C. ;

Bell, E. ;

Palmour, N. ;

Pike, B. ;

Doyon, J. ;

Racine, E. .

JOURNAL OF EMPIRICAL RESEARCH ON HUMAN RESEARCH ETHICS, 2010, 5 (01) :49-66

[2] Handling incidental findings in neuroimaging research in Japan: current state of research facilities and attitudes of investigators and the general population [J].

Fujita, Misao ;

Hayashi, Yoshinori ;

Tashiro, Shimon ;

Takashima, Kyoko ;

Nakazawa, Eisuke ;

Akabayashi, Akira .

HEALTH RESEARCH POLICY AND SYSTEMS, 2014, 12

[3] Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis [J].

Gibson, Lorna M. ;

Paul, Laura ;

Chappell, Francesca M. ;

Macleod, Malcolm ;

Whiteley, William N. ;

Salman, Rustam Al-Shahi ;

Wardlaw, Joanna M. ;

Sudlow, Cathie L. M. .

BMJ-BRITISH MEDICAL JOURNAL, 2018, 363

[4] A Just Standard: The Ethical Management of Incidental Findings in Brain Imaging Research [J].

Graham, Mackenzie ;

Hallowell, Nina ;

Savulescu, Julian .

JOURNAL OF LAW MEDICINE & ETHICS, 2021, 49 (02) :269-281

[5] Incidental Findings Are Frequent in Young Healthy Individuals Undergoing Magnetic Resonance Imaging in Brain Research Imaging Studies: A Prospective Single-Center Study [J].

Hartwigsen, Gesa ;

Siebner, Hartwig R. ;

Deuschl, Guenther ;

Jansen, Olav ;

Ulmer, Stephan .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2010, 34 (04) :596-600

[6] 'Pandora's box' of incidental findings in brain imaging research [J].

Illes, J .

NATURE CLINICAL PRACTICE NEUROLOGY, 2006, 2 (02) :60-61

[7] Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis [J].

Morris, Zoe ;

Whiteley, William N. ;

Longstreth, W. T., Jr. ;

Weber, Frank ;

Lee, Yi-Chung ;

Tsushima, Yoshito ;

Alphs, Hannah ;

Ladd, Susanne C. ;

Warlow, Charles ;

Wardlaw, Joanna M. ;

Salman, Rustam Al-Shahi .

BMJ-BRITISH MEDICAL JOURNAL, 2009, 339 :547-550

[8] Grey Matter - The Problems of Incidental Findings in Neuroimaging Research [J].

Murphy, Nicholas ;

Weijer, Charles .

JOURNAL OF LAW MEDICINE & ETHICS, 2021, 49 (02) :282-284

[9] Impact of incidental findings on young adult participants in brain imaging research: an interview study [J].

Oerlemans, Anke J. M. ;

Barendregt, Danielle M. H. ;

Kooijman, Sabine C. ;

Bunnik, Eline M. .

EUROPEAN RADIOLOGY, 2022, 32 (06) :3839-3845

[10] Acting on incidental findings in research imaging [J].

Wardlaw, J. M. ;

Davies, H. ;

Booth, T. C. ;

Laurie, G. ;

Compston, A. ;

Freeman, C. ;

Leach, M. O. ;

Waldman, A. D. ;

Lomas, D. J. ;

Kessler, K. ;

Crabbe, F. ;

Jackson, A. .

BMJ-BRITISH MEDICAL JOURNAL, 2015, 351

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