Hematopoiesis from human embryonic stem cells

被引:8
作者
Bhatia, Mickie [1 ]
机构
[1] McMaster Univ, Michael G Degroote Sch Med, Stem Cell & Canc Res Inst, Hamilton, ON L8N 3Z5, Canada
来源
HEMATOPOIETIC STEM CELLS VI | 2007年 / 1106卷
关键词
human embryonic stem cells (hESCs); repopulation; hematopoiesis; development; differentiation; hematopoietic stem cells (HSCS);
D O I
10.1196/annals.1392.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Human embryonic-stem cells (hESCs) have the capacity to differentiate into multiple lineages, such as neural and hepatic, and include the ability to form hematopoietic cells. Efforts to develop efficient methods to induce hematopoietic differentiation effectively from hESCs, and generate primitive blood stem cells with multilineage hematopoietic repopulating function, are ongoing in several laboratories. Here, we will discuss the past and current progress of our laboratory in this area, and share our ideas to further this use of hESCs in both experimental and clinical hematology.
引用
收藏
页码:219 / 222
页数:4
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