Architectures of neuronal circuits

被引:165
作者
Luo, Liqun [1 ,2 ]
机构
[1] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
[2] Stanford Univ, Howard Hughes Med Inst, Stanford, CA 94305 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
NERVOUS-SYSTEM; MOSAIC ANALYSIS; PATTERN; SINGLE; EXPRESSION; EVOLUTION; NETWORKS; TASTE; ORGANIZATION; INTERNEURONS;
D O I
10.1126/science.abg7285
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Although individual neurons are the basic unit of the nervous system, they process information by working together in neuronal circuits with specific patterns of synaptic connectivity. Here, I review common circuit motifs and architectural plans used in diverse brain regions and animal species. I also consider how these circuit architectures assemble during development and might have evolved. Understanding how specific patterns of synaptic connectivity can implement specific neural computations will help to bridge the huge gap between the biology of the individual neuron and the function of the entire brain, allow us to better understand the neural basis of behavior, and may inspire new advances in artificial intelligence.
引用
收藏
页码:1103 / +
页数:10
相关论文
共 50 条
  • [21] BAcTrace, a tool for retrograde tracing of neuronal circuits in Drosophila
    Cachero, Sebastian
    Gkantia, Marina
    Bates, Alexander S.
    Frechter, Shahar
    Blackie, Laura
    McCarthy, Amy
    Sutcliffe, Ben
    Strano, Alessio
    Aso, Yoshinori
    Jefferis, Gregory S. X. E.
    [J]. NATURE METHODS, 2020, 17 (12) : 1254 - +
  • [22] Neocortical Evolution: Neuronal Circuits Arise Independently of Lamination
    Karten, Harvey J.
    [J]. CURRENT BIOLOGY, 2013, 23 (01) : R12 - R15
  • [23] Excitatory and Inhibitory Neuronal Circuits in the Spinal Cord and Their Role in the Control of Motor Neuron Function and Degeneration
    Nimrod Ramirez-Jarquin, Uri
    Tapia, Ricardo
    [J]. ACS CHEMICAL NEUROSCIENCE, 2018, 9 (02): : 211 - 216
  • [24] A simple method of in vitro electroporation allows visualization, recording, and calcium imaging of local neuronal circuits
    Hovis, Kenneth R.
    Padmanabhan, Krishnan
    Urban, Nathaniel N.
    [J]. JOURNAL OF NEUROSCIENCE METHODS, 2010, 191 (01) : 1 - 10
  • [25] Expression and function of nicotinic acetylcholine receptors in specific neuronal populations: Focus on striatal and prefrontal circuits
    Abbondanza, Alice
    Urushadze, Anna
    Alves-Barboza, Amanda Rosanna
    Janickova, Helena
    [J]. PHARMACOLOGICAL RESEARCH, 2024, 204
  • [26] Temporal Characterization of Neuronal Migration Behavior on Chemically Patterned Neuronal Circuits in a Defined in Vitro Environment
    Natarajan, Anupama
    Smith, Alec S. T.
    Berry, Bonnie
    Lambert, Stephen
    Molnar, Peter
    Hickman, James J.
    [J]. ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 4 (10): : 3460 - 3470
  • [27] Development of motor circuits: From neuronal stem cells and neuronal diversity to motor circuit assembly
    Meng, Julia L.
    Heckscher, Ellie S.
    [J]. MOLECULAR MECHANISMS OF NEURAL DEVELOPMENT AND INSIGHTS INTO DISEASE, 2021, 142 : 409 - 442
  • [28] Neuronal circuits integrating visual motion information in Drosophila melanogaster
    Shinomiya, Kazunori
    Nern, Aljoscha
    Meinertzhagen, Ian A.
    Plaza, Stephen M.
    Reiser, Michael B.
    [J]. CURRENT BIOLOGY, 2022, 32 (16) : 3529 - +
  • [29] Neuronal Circuits Involved in the Middle-Ear Acoustic Reflex
    Venet, Thomas
    Rumeau, Cecile
    Campo, Pierre
    Rieger, Benoit
    Thomas, Aurelie
    Cour, Chantal
    [J]. TOXICOLOGICAL SCIENCES, 2011, 119 (01) : 146 - 155
  • [30] Neuronal Circuits That Control Rhythmic Pectoral Fin Movements in Zebrafish
    Uemura, Yuto
    Kato, Kagayaki
    Kawakami, Koichi
    Kimura, Yukiko
    Oda, Yoichi
    Higashijima, Shin-ichi
    [J]. JOURNAL OF NEUROSCIENCE, 2020, 40 (35) : 6678 - 6690