Lymphatics in lung disease

被引：58

作者：

El-Chemaly, Souheil ^{[1
]}

Levine, Stewart J. ^{[1
]}

Moss, Joel ^{[1
]}

机构：

[1] NHLBI, Translat Med Branch, NIH, Bethesda, MD 20892 USA

来源：

LYMPHATIC CONTINUUM REVISITED | 2008年 / 1131卷

关键词：

lymphangiogenesis; metastasis; lymphangiectasis; lymphangioleiomyomatosis; VEGF-D; VEGF-C;

D O I：

10.1196/annals.1413.017

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The lymphatic circulation appears to be a vital component in lung biology in health and in disease. Animal models have established the role of the lymphatic circulation in neoplastic and inflammatory diseases of the lung, such as asthma and cancer, and allowed for the understanding of the molecular controls of lymphangiogenesis in normal lung development. Understanding the role of lymphatics in human lung disease appears likely to contribute to the understanding of the pathogenesis of disease and the development of novel therapeutic targets.

引用

页码：195 / 202

页数：8

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