Functional Imaging Computed Tomography and MRI

被引:13
作者
Mirsadraee, Saeed [1 ]
van Beek, Edwin J. R. [1 ]
机构
[1] Univ Edinburgh, Queens Med Res Inst, Clin Res Imaging Ctr, Edinburgh EH16 4TJ, Midlothian, Scotland
关键词
CT; Airways; Parenchyma; Ventilation; Perfusion; Computer-aided detection; Lung function; MRI; DUAL-ENERGY CT; THROMBOEMBOLIC PULMONARY-HYPERTENSION; HE-3; MAGNETIC-RESONANCE; PERFUSION CT; QUANTITATIVE ASSESSMENT; BLOOD-VOLUME; LUNG; VENTILATION; XENON; EMPHYSEMA;
D O I
10.1016/j.ccm.2015.02.014
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Standard imaging for the lungs allow excellent visualization of normal and abnormal pulmonary patterns. Computed tomography (CT), however, has limitations. The recognized patterns have limited specificity, do not always diagnose the pathology at a treatable stage, and do not provide physiologic information. Advances allow more physiologic approaches in lung imaging, namely, functional imaging. The main functional lung imaging modalities are CT and MRI. Contrast and noncontrast imaging approaches study pulmonary perfusion, dynamics of the flow in the pulmonary artery, and motion. Noble gases allow assessment of regional pulmonary ventilation. We discuss the role of novel imaging techniques in the functional lung assessment.
引用
收藏
页码:349 / +
页数:16
相关论文
共 87 条
[21]   Dual-Energy CT Angiography of the Lung in Patients with Suspected Pulmonary Embolism: Initial Results [J].
Fink, C. ;
Johnson, T. R. ;
Michaely, H. J. ;
Morhard, D. ;
Becker, C. ;
Reiser, M. ;
Nikolaou, K. .
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2008, 180 (10) :879-883
[22]   Optimization of Dual-Energy Xenon-Computed Tomography for Quantitative Assessment of Regional Pulmonary Ventilation [J].
Fuld, Matthew K. ;
Halaweish, Ahmed F. ;
Newell, John D., Jr. ;
Krauss, Bernhard ;
Hoffman, Eric A. .
INVESTIGATIVE RADIOLOGY, 2013, 48 (09) :629-637
[23]   Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression [J].
Galban, Craig J. ;
Han, Meilan K. ;
Boes, Jennifer L. ;
Chughtai, Komal A. ;
Meyer, Charles R. ;
Johnson, Timothy D. ;
Galban, Stefanie ;
Rehemtulla, Alnawaz ;
Kazerooni, Ella A. ;
Martinez, Fernando J. ;
Ross, Brian D. .
NATURE MEDICINE, 2012, 18 (11) :1711-+
[24]   Xenon ventilation CT using dual-source and dual-energy technique in children with bronchiolitis obliterans: correlation of xenon and CT density values with pulmonary function test results [J].
Goo, Hyun Woo ;
Yang, Dong Hyun ;
Hong, Soo-Jong ;
Yu, Jinho ;
Kim, Byoung-Ju ;
Seo, Joon Beom ;
Chae, Eun Jin ;
Lee, Jeongjin ;
Krauss, Bernhard .
PEDIATRIC RADIOLOGY, 2010, 40 (09) :1490-1497
[25]   Ultralow-Dose Chest Computed Tomography for Pulmonary Nodule Detection First Performance Evaluation of Single Energy Scanning With Spectral Shaping [J].
Gordic, Sonja ;
Morsbach, Fabian ;
Schmidt, Bernhard ;
Allmendinger, Thomas ;
Flohr, Thomas ;
Husarik, Daniela ;
Baumueller, Stephan ;
Raupach, Rainer ;
Stolzmann, Paul ;
Leschka, Sebastian ;
Frauenfelder, Thomas ;
Alkadhi, Hatem .
INVESTIGATIVE RADIOLOGY, 2014, 49 (07) :465-473
[26]   PERFUSION QUANTITATION BY ULTRAFAST COMPUTED-TOMOGRAPHY [J].
GOULD, RG .
INVESTIGATIVE RADIOLOGY, 1992, 27 :S18-S21
[27]   Quantification of Tortuosity and Fractal Dimension of the Lung Vessels in Pulmonary Hypertension Patients [J].
Helmberger, Michael ;
Pienn, Michael ;
Urschler, Martin ;
Kullnig, Peter ;
Stollberger, Rudolf ;
Kovacs, Gabor ;
Olschewski, Andrea ;
Olschewski, Horst ;
Balint, Zoltan .
PLOS ONE, 2014, 9 (01)
[28]   Radiation Risks of Medical Imaging: Separating Fact from Fantasy [J].
Hendee, William R. ;
O'Connor, Michael K. .
RADIOLOGY, 2012, 264 (02) :312-321
[29]   Large production system for hyperpolarized 129Xe for human lung imaging studies [J].
Hersman, F. William ;
Ruset, Iulian C. ;
Ketel, Stephen ;
Muradian, Iga ;
Covrig, Silviu D. ;
Distelbrink, Jan ;
Porter, Walter ;
Watt, David ;
Ketel, Jeffrey ;
Brackett, John ;
Hope, Aaron ;
Patz, Samuel .
ACADEMIC RADIOLOGY, 2008, 15 (06) :683-692
[30]   Dual-Energy CT Angiography for Assessment of Regional Pulmonary Perfusion in Patients With Chronic Thromboembolic Pulmonary Hypertension: Initial Experience [J].
Hoey, Edward T. D. ;
Mirsadraee, Saeed ;
Pepke-Zaba, Joanna ;
Jenkins, David P. ;
Gopalan, Deepa ;
Screaton, Nicholas J. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2011, 196 (03) :524-532