New Insights for Exploring the Risks of Bioaccumulation, Molecular Mechanisms, and Cellular Toxicities of AgNPs in Aquatic Ecosystem

被引：27

作者：

Ramzan, Uzma ^{[1
]}

Majeed, Waqar ^{[2
]}

Hussain, Abdul Ahad ^{[3
]}

Qurashi, Fasiha ^{[4
]}

Qamar, Safi Ur Rehman ^{[5
]}

Naeem, Muhammad ^{[6
]}

Uddin, Jalal ^{[7
]}

Khan, Ajmal ^{[8
]}

Al-Harrasi, Ahmed ^{[8
]}

Abd Razak, Saiful Izwan ^{[9
,10
]}

Lee, Tze Yan ^{[11
,12
]}

机构：

[1] Univ Punjab, Inst Zool, Quaid E Azam Campus, Lahore 54000, Pakistan

[2] Univ Agr Faisalabad, Dept Zool Wildlife & Fisheries, Faisalabad 38040, Pakistan

[3] Univ Agr Faisalabad, Dept Phys, Faisalabad 38040, Pakistan

[4] Islamia Univ Bahawalpur, Dept Forestry Range & Wildlife Management, Bahawalpur 63100, Pakistan

[5] Chulabhorn Grad Inst, Appl Biol Sci Program, 54 Kamphaeng Phet 6 Rd, Bangkok 10210, Thailand

[6] Hebei Normal Univ, Coll Life Sci, Shijiazhuang 050024, Hebei, Peoples R China

[7] King Khalid Univ, Coll Pharm, Dept Pharmaceut Chem, Abha 62529, Saudi Arabia

[8] Univ Nizwa, Nat & Med Sci Res Ctr, POB 33, Birkat Al Mauz 616, Nizwa, Oman

[9] Univ Teknol Malaysia, Fac Engn, Sch Biomed Engn & Hlth Sci, BioInspired Device & Tissue Engn Res Grp, Johor Baharu 81310, Malaysia

[10] Univ Teknol Malaysia, Sports Innovat & Technol Ctr, Inst Human Centred Engn, Johor Baharu 81310, Malaysia

[11] Perdana Univ, Sch Liberal Arts Sci & Technol PUScLST, Suite 9-2,9th Floor, Kuala Lumpur 50490, Malaysia

[12] INTI Int Univ, Ctr Inst Anal & Dev, Persiaran Perdana BBN, Nilai 71800, Negeri Sembilan, Malaysia

来源：

WATER | 2022年 / 14卷 / 14期

关键词：

AgNPs; marine ecosystem; toxicity; bioaccumulation; pollutants; molecular mechanisms; SILVER NANOPARTICLES; ENGINEERED NANOPARTICLES; OXIDATIVE STRESS; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; IN-VITRO; GOLD NANOPARTICLES; NEW-GENERATION; ION RELEASE; ZEBRAFISH;

D O I：

10.3390/w14142192

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Silver nanoparticles (AgNPs) are commonly used in numerous consumer products, including textiles, cosmetics, and health care items. The widespread usage of AgNPs results in their unavoidable discharge into the ecosystem, which pollutes the aquatic, groundwater, sediments, and marine environments. These nanoparticles (NPs) activate the production of free radicals reactive species in aquatic organisms that interrupt the functions of DNA, cause mitochondrial dysfunction, and increase lipid peroxidation, which terminates the development and reproduction both in vivo and in vitro. The life present in the aquatic ecosystem is becoming threatened due to the release and exploitation of AgNPs. Managing the aquatic ecosystem from the AgNP effects in the near future is highly recommended. In this review, we discussed the background of AgNPs, their discharge, and uptake by aquatic organisms, the mechanism of toxicity, different pathways of cytotoxicity, and bioaccumulation, particularly in aquatic organisms. We have also discussed the antimicrobial activities of AgNPs along with acute and chronic toxicity in aquatic groups of organisms.

引用

页数：23

共 185 条

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