Orofacial granulomatosis associated with hypersensitivity to dental amalgam

被引：8

作者：

Tomka, Milan ^{[1
,2
]}

Machovcova, Alena

Pelclova, Daniela ^{[2
,3
]}

Petanova, Jitka ^{[2
,4
]}

Arenbergerova, Monika ^{[5
,6
]}

Prochazkova, Jarmila ^{[1
,2
]}

机构：

[1] Charles Univ Prague, Fac Med 1, Inst Dent Res, Prague 12111 2, Czech Republic

[2] Gen Univ Hosp, Prague, Czech Republic

[3] Charles Univ Prague, Fac Med 1, Dept Occupat Med, Prague 12111 2, Czech Republic

[4] Charles Univ Prague, Fac Med 1, Inst Microbiol & Immunol, Prague 12111 2, Czech Republic

[5] Charles Univ Prague, Fac Med 3, Dept Dermatovenereol, Prague 12111 2, Czech Republic

[6] Teaching Hosp Kralovske Vinohrady, Kralovske, Russia

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2011年 / 112卷 / 03期

关键词：

LYMPHOCYTE-TRANSFORMATION TEST; ORO-FACIAL GRANULOMATOSIS; DELAYED-HYPERSENSITIVITY; DIAGNOSTIC-VALUE; ALLERGY; MERCURY; NICKEL; GOLD; SENSITIVITY; SARCOIDOSIS;

D O I：

10.1016/j.tripleo.2011.03.030

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Orofacial granulomatosis is a clinicopathologic entity characterized by chronic swelling of the lip and possible soft tissues in the orofacial region owing to granulomatous inflammation of unknown cause. We present 3 cases of orofacial granulomatosis associated with allergic contact dermatitis to dental materials. Previous treatment with corticosteroids did not have any therapeutic effect. Patch testing revealed a positive reaction to several allergens, including dental amalgam and mercury in 2 cases. A lymphocyte transformation test modified for metals was used to evaluate lymphocyte reactivity. After the removal of the suspected allergens, all patients experienced recovery within 1 month, with the exception of the lip swelling, which gradually subsided over several months. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 335-341)

引用

页码：335 / 341

页数：7

共 30 条

[21] The lymphocyte transformation test in the diagnosis of drug hypersensitivity [J].