Orofacial granulomatosis associated with hypersensitivity to dental amalgam

被引：8
作者：
Tomka, Milan [1 ,2 ]
Machovcova, Alena
Pelclova, Daniela [2 ,3 ]
Petanova, Jitka [2 ,4 ]
Arenbergerova, Monika [5 ,6 ]
Prochazkova, Jarmila [1 ,2 ]
机构：
[1] Charles Univ Prague, Fac Med 1, Inst Dent Res, Prague 12111 2, Czech Republic
[2] Gen Univ Hosp, Prague, Czech Republic
[3] Charles Univ Prague, Fac Med 1, Dept Occupat Med, Prague 12111 2, Czech Republic
[4] Charles Univ Prague, Fac Med 1, Inst Microbiol & Immunol, Prague 12111 2, Czech Republic
[5] Charles Univ Prague, Fac Med 3, Dept Dermatovenereol, Prague 12111 2, Czech Republic
[6] Teaching Hosp Kralovske Vinohrady, Kralovske, Russia
来源：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2011年 / 112卷 / 03期
关键词：
LYMPHOCYTE-TRANSFORMATION TEST; ORO-FACIAL GRANULOMATOSIS; DELAYED-HYPERSENSITIVITY; DIAGNOSTIC-VALUE; ALLERGY; MERCURY; NICKEL; GOLD; SENSITIVITY; SARCOIDOSIS;
D O I：
10.1016/j.tripleo.2011.03.030
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Orofacial granulomatosis is a clinicopathologic entity characterized by chronic swelling of the lip and possible soft tissues in the orofacial region owing to granulomatous inflammation of unknown cause. We present 3 cases of orofacial granulomatosis associated with allergic contact dermatitis to dental materials. Previous treatment with corticosteroids did not have any therapeutic effect. Patch testing revealed a positive reaction to several allergens, including dental amalgam and mercury in 2 cases. A lymphocyte transformation test modified for metals was used to evaluate lymphocyte reactivity. After the removal of the suspected allergens, all patients experienced recovery within 1 month, with the exception of the lip swelling, which gradually subsided over several months. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 335-341)
引用
收藏
页码：335 / 341
页数：7
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