Acute respiratory distress syndrome induced by rifampicin with high levels of neutrophil and eosinophil products in bronchoalveolar lavage fluid

被引：10

作者：

Ashitani, J

Yanagi, S

Arimura, Y

Sano, A

Mukae, H

机构：

[1] Miyazaki Med Coll, Dept Internal Med 3, Miyazaki 8891692, Japan

[2] Nagasaki Univ, Sch Med, Dept Internal Med 2, Nagasaki 852, Japan

来源：

RESPIRATION | 2003年 / 70卷 / 05期

关键词：

ARDS; rifampicin; pulmonary tuberculosis; BAL; eosinophil;

D O I：

10.1159/000074216

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

We reported a case with acute respiratory distress syndrome (ARDS) caused by rifampicin during therapy for pulmonary tuberculosis. A high level of eosinophil cationic protein in bronchoalveolar lavage fluid (BALF) was detected as well as interleukin-8 and neutrophil elastase. Based on these results together with the positive result of the drug lymphocyte-stimulating test, we concluded that rifampicin was the causative drug leading to ARDS. Corticosteroid therapy resulted in clinical improvement and resolution of the pulmonary infiltrates on the chest radiograph without the recurrence of pulmonary tuberculosis. Copyright (C) 2003 S. Karger AG, Basel.

引用

页码：541 / 543

页数：3

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