Phytotoxicity reduction of the mercury chloride effect by natural products from Eugenia jambolana Lam.: A new strategy against the toxic metal pollution

被引：7

作者：

Sobral-Souza, Celestina E. ^{[1
]}

Silva, Ana R. P. ^{[1
]}

Leite, Nadghia F. ^{[1
]}

Rocha, Janaina E. ^{[1
]}

Sousa, Amanda K. ^{[1
]}

Costa, Jose G. M. ^{[2
]}

Menezes, Irwin R. A. ^{[3
]}

Cunha, Francisco A. B. ^{[1
]}

Rolim, Larissa A. ^{[4
]}

Coutinho, Henrique D. M. ^{[1
]}

机构：

[1] Univ Reg Cariri, Lab Microbiol & Biol Mol, Rua Cel Antonio Luis 1161, BR-63105000 Crato, CE, Brazil

[2] Univ Reg Cariri, Lab Pesquisa Prod Nat, Crato, CE, Brazil

[3] Univ Reg Cariri, Lab Farmacol & Quim Mol, Crato, CE, Brazil

[4] Univ Fed Vale Sao Francisco, Cent Anal Farmacos Med & Alimentos, Petrolina, PE, Brazil

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2019年 / 170卷

关键词：

Antioxidant; Cytoprotection; Mercury chloride; Eugenia jambolana; ANTIOXIDANT ACTIVITY; MASS-SPECTROMETRY; PHENOLIC-COMPOUNDS; SYZYGIUM-CUMINI; FLAVONOIDS; EXTRACTS; MS;

D O I：

10.1016/j.ecoenv.2018.12.007

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The objective of this work was to evaluate the antioxidant, metal chelating and cytoprotective activity of the Eugenia jambolana Lam. extract, as well as of its flavonoid and tannic fractions, against the action of Mercury Chloride (HgCl2). Flavonoids were quantified and an LC-MS chromatographic analysis was performed to identify secondary metabolites. Fe2+ and Fe3+ chelation tests and antioxidant activity were carried out using the FRAP method. Microbiological tests were performed by microdilution to determine the Minimum Inhibitory Concentration (MIC). From these results the Minimum Bactericidal (MBC) and Minimum Fungicide Concentration (MFC) were evaluated. The allelopathy and cytoprotection assays were performed using eukaryotic and prokaryotic models. The results revealed the presence of phenolic acids and flavonoids in the E. jambolana extract and fractions. The sub-allelopathic concentration (64 mu g/mL) was used and the results demonstrated the E. jambolana potential cytoprotective effect against mercury chloride.

引用

页码：461 / 467

页数：7

共 4 条

[1] Cytoprotective effect against mercury chloride and bioinsecticidal activity of Eugenia jambolana Lam.
Sobral-Souza, Celestina E.
Leite, Nadghia F.
Cunha, Francisco A. B.
Pinho, Antonio I.
Albuquerque, Rosimeire S.
Carneiro, Joara N. P.
Menezes, Irwin R. A.
Costa, Jose G. M.
Franco, Jeferson L.
Coutinho, Henrique D. M.
ARABIAN JOURNAL OF CHEMISTRY, 2014, 7 (01) : 165 - 170
[2] LC-MS characterization and reduction of the phytotoxic effect of aluminium by natural products from Eugenia jambolana Lam.
Sousa, Amanda K.
Sobral-Souza, Celestina E.
Ralim, Larissa A.
Silva, Ana R. P.
Leite, Nadghia F.
Rocha, Janaina E.
Coutinho, Henrique D. M.
APPLIED GEOCHEMISTRY, 2018, 98 : 191 - 196
[3] LC–MS characterization, anti-kinetoplastide and cytotoxic activities of natural products from Eugenia jambolana Lam. and Eugenia uniflora
Celestina Elba Sobral de Souza
Ana Raquel Pereira da Silva
Janaina Esmeraldo Rocha
Maria Celeste Vega Gomez
Míriam Rolóm
Cathia Coronel
José Galberto Martins da Costa
Manoel L.C.Netto
Larissa A.Rolim
Henrique Douglas Melo Coutinho
Asian Pacific Journal of Tropical Biomedicine, 2017, (09) : 836 - 841
[4] LC-MS characterization, anti-kinetoplastide and cytotoxic activities of natural products from Eugenia jambolana Lam. and Eugenia uniflora
Sobral de Souza, Celestina Elba
Pereira da Silva, Ana Raquel
Rocha, Janaina Esmeraldo
Vega Gomez, Maria Celeste
Rolom, Miriam
Coronel, Cathia
Martins da Costa, Jose Galberto
Netto, Manoel L. C.
Rolim, Larissa A.
Melo Coutinho, Henrique Douglas
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, 2017, 7 (09) : 836 - 841

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