An unusual dihydrobenzofuroisocoumarin and ent-kaurane diterpenoids from Pteris multifida

被引：10

作者：

Ni, Gang ^{[1
,2
]}

Fu, Nai-Jie ^{[1
,2
]}

Zhang, Di ^{[1
,2
]}

Yang, Han-Ze ^{[1
,2
]}

Chen, Xiao-Guang ^{[1
,2
]}

Yu, De-Quan ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Inst Mat Med, Beijing 100050, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2015年 / 17卷 / 05期

基金：

中国国家自然科学基金;

关键词：

multifidarin A; Pteridaceae; Pteris multifida; isocoumarin; multikaurane; ent-kaurane diterpenoids; CRETICA L; CONSTITUENTS; ISOCOUMARINS; DERIVATIVES; POIR;

D O I：

10.1080/10286020.2015.1040777

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

An unusual 5-C-methylated-dihydrobenzofuroisocoumarin, named multifidarin A (1), and two new ent-kaurane diterpenoids, named multikauranes A (2) and B (3), together with three known ent-kaurane diterpenoids, were isolated from the whole plants of Pteris multifida. The structures of 1-3 were elucidated by spectroscopic methods. The cytotoxic activities of all new compounds were evaluated against five human tumor cell lines. A possible biosynthetic process for the formation of 1 is proposed.

引用

页码：423 / 429

页数：7

共 18 条

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