Agitation after traumatic brain injury - Considerations and treatment options

被引:85
作者
Lombard, LA [1 ]
Zafonte, RD [1 ]
机构
[1] Univ Pittsburgh, Med Ctr, Inst Rehabil & Res, Dept Phys Med & Rehabil, Pittsburgh, PA 15213 USA
关键词
traumatic brain injury; agitation; delirium; behavior;
D O I
10.1097/01.phm.0000179438.22235.08
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Lombard LA, Zafonte RD: Agitation after traumatic brain injury: Considerations and treatment options. Am J Phys Med Rehabil 2005;84:797-812. Posttraumatic agitation is a challenging problem for acute and rehabilitation staff, persons with traumatic brain injury, and their families. Specific variables for evaluation and care remain elusive. Clinical trials have not yielded a strong foundation for evidence-based practice in this arena. This review seeks to evaluate the present literature (with a focus on the decade 1995-2005) and employ previous clinical experience to deliver a review of the topic. We will discuss definitions, pathophysiology, evaluation techniques, and treatment regimens. A recommended approach to the evaluation and treatment of the person with posttraumatic agitation will be presented. The authors hope that this review will spur discussion and assist in facilitating clinical care paradigms and research programs.
引用
收藏
页码:797 / 812
页数:16
相关论文
共 154 条
[1]  
ADLER LA, 1991, PSYCHOPHARMACOL BULL, V27, P107
[2]   Neuroendocrine dysfunction in the acute phase of traumatic brain injury [J].
Agha, A ;
Rogers, B ;
Mylotte, D ;
Taleb, F ;
Tormey, W ;
Phillips, J ;
Thompson, CJ .
CLINICAL ENDOCRINOLOGY, 2004, 60 (05) :584-591
[3]   THE SEPTAL FOREBRAIN AND THE INHIBITORY MODULATION OF ATTACK AND DEFENSE IN THE RAT - A REVIEW [J].
ALBERT, DJ ;
CHEW, GL .
BEHAVIORAL AND NEURAL BIOLOGY, 1980, 30 (04) :357-388
[4]   Predisposing factors for delirium in the surgical intensive care unit [J].
Aldemir, M ;
Özen, S ;
Kara, IH ;
Sir, A ;
Baç, B .
CRITICAL CARE, 2001, 5 (05) :265-270
[5]   Aggressive behaviour observed within a neurobehavioural rehabilitation service: utility of the OAS-MNR in clinical audit and applied research [J].
Alderman, N ;
Knight, C ;
Henman, CL .
BRAIN INJURY, 2002, 16 (06) :469-489
[6]   Use of a modified version of the Overt Aggression Scale in the measurement and assessment of aggressive behaviours following brain injury [J].
Alderman, N ;
Knight, C ;
Morgan, C .
BRAIN INJURY, 1997, 11 (07) :503-523
[7]  
Alderman N, 1999, BRAIN INJURY, V13, P669
[8]   Increases in metabolism of valproate and excretion of 6β-hydroxycortisol in patients with traumatic brain injury [J].
Anderson, GD ;
Awan, AB ;
Adams, CA ;
Temkin, NR ;
Winn, HR .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1998, 45 (02) :101-105
[9]   Agitation assessment in severe traumatic brain injury: methodological and clinical issues [J].
Angelino, E ;
Miglioretti, M ;
Zotti, AM .
BRAIN INJURY, 2002, 16 (03) :269-275
[10]   Amantadine for neurobehavioural deficits following delayed post-hypoxic encephalopathy [J].
Arciniegas, DB ;
Frey, KL ;
Anderson, CA ;
Brousseau, KM ;
Harris, SN .
BRAIN INJURY, 2004, 18 (12) :1309-1318