Two New Pentacyclic Triterpenoids from Centella asiatica

被引：10

作者：

Weng, Xiao-Xiang ^{[1
]}

Zhang, Jing ^{[1
]}

Gao, Wen ^{[1
]}

Cheng, Liang ^{[1
]}

Shao, Yan ^{[1
]}

Kong, De-Yun ^{[1
]}

机构：

[1] Shanghai Inst Pharmaceut Ind, Dept Chinese Tradit Med, Shanghai 200040, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2012年 / 95卷 / 02期

关键词：

Centella asiatica; Centellosides D and E; Cytotoxic activity; Triterpenoids; Glycosides; GLYCOSIDES; OLEANANE; SAPONIN;

D O I：

10.1002/hlca.201100287

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new pentacyclic triterpenoids, named centelloside D (1) and centelloside E (9), together with the seven known compounds 28, were isolated from the whole plants of Centella asiatica. Compound 5 was reported for the first time from this genus. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D- and 2D-NMR, and HR-MS experiments, and by comparison with literature data. Compounds 14, 6, and 8 did not show any cytotoxicity against L929 (mouse embryonic fibroblast).

引用

页码：255 / 260

页数：6

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