Biomedical Applications of Superparamagnetic Nanoparticles in Molecular Scale

被引：8

作者：

Rahman, Masoud ^{[1
]}

Saei, Amir A. ^{[2
,3
,4
]}

Amiri, Houshang ^{[5
,6
]}

Mahmoudi, Morteza ^{[3
,7
]}

机构：

[1] Univ Calif Davis, Dept Chem Engn & Mat Sci, Davis, CA 95616 USA

[2] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[3] Univ Tehran Med Sci, Fac Pharm, Dept Nanotechnol, Tehran, Iran

[4] Karolinska Inst, Dept Med Biochem & Biophys, Stockholm, Sweden

[5] Kerman Univ Med Sci, Neurosci Res Ctr, Inst Neuropharmacol, Kerman, Iran

[6] Radboud Univ Nijmegen, Med Ctr, Dept Radiol, NL-6525 ED Nijmegen, Netherlands

[7] Stanford Univ, Sch Med, Div Cardiovasc Med, Stanford, CA 94305 USA

来源：

CURRENT ORGANIC CHEMISTRY | 2015年 / 19卷 / 11期

关键词：

Detection; imaging; magnetic nanoparticle; protein separation; sensing; targeted delivery; toxin decorporation; IRON-OXIDE NANOPARTICLES; FUNCTIONALIZED MAGNETIC NANOPARTICLES; NEURAL STEM-CELLS; IN-VIVO; PROTEIN CORONA; HIGHLY EFFICIENT; REUSABLE CATALYST; CONJUGATED NANOPARTICLES; RECYCLABLE CATALYST; FE3O4; NANOPARTICLES;

D O I：

10.2174/138527281911150610100548

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Magnetic nanoparticles and especially superparamagnetic iron oxide nanoparticles (SPIONs) have found innumerable applications in bioscience and biotechnology. Accommodation of active molecules and forming homogeneous dispersion in solution, combined with easy capture by external magnetic fields has made them favorable candidates for molecular scale applications such as sensing and detection, imaging, targeted delivery, toxin decorporation, catalysis and pathogen removal. This review summarizes the recent advances and challenges in the above-mentioned applications.

引用

页码：982 / 990

页数：9

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