Statistical atlas of acute stroke from magnetic resonance diffusion-weighted-images of the brain

被引:7
作者
Bilello, Michel [1 ]
Lao, Zhiqiang [1 ]
Krejza, Jaroslaw [1 ,2 ]
Hillis, Argye E. [2 ]
Herskovits, Edward H. [1 ]
机构
[1] Hosp Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[2] Med Univ Gdansk, Dept Radiol, Gdansk, Poland
关键词
stroke; atlas; MRI; diffusion weighted; computer-aided; image processing; statistical;
D O I
10.1385/NI:4:3:235
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
This study presents a method for computing a probabilistic atlas that describes the spatial distributions of acute infarcts of the brain. The data consisted of diffusion-weighted-images (DWI) and high-resolution T1-weighted MR images representing 22 studies from 22 subjects. All DWI data sets contained high-intensity lesions on B-1000 maps, known from clinical history to be related to acute stroke. To compute the atlas, manually segmented infarcts on original DWI were spatially transformed and registered to a common coordinate system. This coordinate system allowed combining all lesions into a statistical atlas in the model space. As a result, the computed probabilistic map showed mild left-sided predominance of brain infarcts, which likely represents asymmetry in eloquence of brain regions. In our opinion, the statistical atlas of acute brain infarcts can facilitate computer-based detection of stroke in large image data sets.
引用
收藏
页码:234 / 242
页数:8
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