Disability in elderly people with multiple sclerosis: An analysis of baseline data from the Sonya Slifka Longitudinal Multiple Sclerosis Study

被引:0
作者
Minden, SL
Frankel, D
Hadden, LS
Srinath, KP
Perloff, JN
机构
[1] Abt Associates Inc, Cambridge, MA 02138 USA
[2] Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
[3] Brandeis Univ, Heller Sch, Waltham, MA 02254 USA
关键词
multiple sclerosis; aging; disability; chronic illness;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This study compares the demographic, clinical, and health care characteristics of 2,156 persons over and under age 65 who are participants in the Sonya Slifka Longitudinal Multiple Sclerosis Study and examines the effects of current age, age at diagnosis, course, and duration of illness on disability-related outcomes. Compared to younger MS patients, significantly higher percentages of older patients lived alone, had lower incomes, and were severely disabled; 85% needed help with activities of daily living and 40% received home care services. Almost all older patients had health insurance, 75% had prescription drug coverage, and few reported difficulty accessing general medical and specialized MS care; perceptions of health status and quality of life were relatively positive. Duration and course of illness were the major predictors of disability, although older current age and younger age at diagnosis were also associated. The relationship among age- and disease-related variables is complex and they likely exert independent effects on disability-related outcomes. Planning is needed by caregivers and policy makers to ensure that the specialized needs of elderly persons with MS are adequately met.
引用
收藏
页码:55 / 67
页数:13
相关论文
共 50 条
[21]   Smoking and worsening disability in multiple sclerosis: A meta-analysis [J].
Heydarpour, P. ;
Manouchehrinia, A. ;
Beiki, O. ;
Mousavi, S. E. ;
Abdolalizadeh, A. ;
Moradi-Lakeh, M. ;
Sahraian, M. A. .
ACTA NEUROLOGICA SCANDINAVICA, 2018, 138 (01) :62-69
[22]   Multiple sclerosis relapses: a multivariable analysis of residual disability determinants [J].
Vercellino, M. ;
Romagnolo, A. ;
Mattioda, A. ;
Masera, S. ;
Piacentino, C. ;
Merola, A. ;
Chi, A. ;
Mutani, R. ;
Cavalla, P. .
ACTA NEUROLOGICA SCANDINAVICA, 2009, 119 (02) :126-130
[23]   Longitudinal disability curves for predicting the course of relapsing-remitting multiple sclerosis [J].
Achiron, A ;
Barak, Y ;
Rotstein, Z .
MULTIPLE SCLEROSIS, 2003, 9 (05) :486-491
[24]   Gait variability across the disability spectrum in people with multiple sclerosis [J].
Kalron, Alon .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2016, 361 :1-6
[25]   Disability in elderly patients with chronic neurological illness: Stroke, multiple sclerosis and epilepsy [J].
Mollaoglu, Mukadder ;
Fertelli, Tulay Kars ;
Tuncay, Fatma Ozkan .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2011, 53 (02) :E227-E231
[26]   Insights Into Disability and Disability Progression in People With Multiple Sclerosis Using Large-Scale Healthcare Data [J].
Dereli, Onur ;
Behringer, Jochen ;
Berthele, Achim ;
Hapfelmeier, Alexander ;
Hemmer, Bernhard ;
Gasperi, Christiane .
EUROPEAN JOURNAL OF NEUROLOGY, 2025, 32 (04)
[27]   Accumulation of irreversible disability in multiple sclerosis: From epidemiology to treatment [J].
Confavreux, C ;
Vukusic, S .
CLINICAL NEUROLOGY AND NEUROSURGERY, 2006, 108 (03) :327-332
[28]   Development and Internal Validation of a Disability Algorithm for Multiple Sclerosis in Administrative Data [J].
Marrie, Ruth Ann ;
Tan, Qier ;
Ekuma, Okechukwu ;
Marriott, James J. .
FRONTIERS IN NEUROLOGY, 2021, 12
[29]   Validity of patient-derived disability and clinical data in multiple sclerosis [J].
Ingram, G. ;
Colley, E. ;
Ben-Shlomo, Y. ;
Cossburn, M. ;
Hirst, C. L. ;
Pickersgill, T. P. ;
Robertson, N. P. .
MULTIPLE SCLEROSIS JOURNAL, 2010, 16 (04) :472-479
[30]   How is neuromuscular fatigability affected by perceived fatigue and disability in people with multiple sclerosis? [J].
Royer, Nicolas ;
Coates, Kyla ;
Aboodarda, Saied Jalal ;
Camdessanche, Jean-Philippe ;
Millet, Guillaume Y. .
FRONTIERS IN NEUROLOGY, 2022, 13