Toxicology of Frequently Encountered Nonsteroidal Anti-inflammatory Drugs in Dogs and Cats: An Update

被引：23
|
作者：
McLean, Mary Kay [1 ]
Khan, Safdar A. [2 ]
机构：
[1] US Army, Vet Treatment Facil, Bldg 265,10th Div Rd, Ft Benning, GA 31905 USA
[2] Zoetis Anim Hlth, Global Pharmacovigilance, 333 Portage Rd, Kalamazoo, MI 49007 USA
来源：
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2018年 / 48卷 / 06期
关键词：
Toxicology; Nonsteroidal anti-inflammatory drugs; Incidents; Dogs; Cats; Treatment; DICLOFENAC SODIUM VOLTAREN; IBUPROFEN TOXICOSIS; PHARMACOLOGICAL PROPERTIES; THERAPEUTIC EFFICACY; NAPROXEN TOXICOSIS; PERFORATION; CARPROFEN; BIOTRANSFORMATION; TOXICITY; ASPIRIN;
D O I：
10.1016/j.cvsm.2018.06.003
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for their antipyretic, anti-inflammatory, and analgesic properties. Although most NSAIDs consist of a range of pharmacologically active agents with diverse chemical structures and properties, they have similar therapeutic and adverse effects associated with their use. Each year, the American Society for the Prevention of Cruelty to Animals Animal Poison Control Center (APCC) receives hundreds of cases involving acute accidental ingestion/overdose of NSAIDs in dogs and cats. This article provides an overview on the classification, uses, pharmacokinetics, mechanisms of action, and treatment of the most commonly encountered NSAIDs in dogs and cats.
引用
收藏
页码：969 / +
页数：18
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