Evidence-Based Genetic Counseling for Psychiatric Disorders: A Road Map

被引：69
作者：
Austin, Jehannine C. [1 ,2 ,3 ]
机构：
[1] Univ British Columbia, Dept Psychiat, Vancouver, BC V5Z 4H4, Canada
[2] Univ British Columbia, Dept Med Genet, Vancouver, BC V5Z 4H4, Canada
[3] BC Mental Hlth & Subst Use Serv, Res Inst, Columbia, BC V6Z 2A9, Canada
来源：
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE | 2020年 / 10卷 / 06期
关键词：
PSYCHOTIC DISORDERS; INDIVIDUALS; RISK; FAMILIES; SCALE; ERA; SCHIZOPHRENIA; PERCEPTIONS; RELATIVES; PEOPLE;
D O I：
10.1101/cshperspect.a036608
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Psychiatric disorders, such as schizophrenia, depression, anxiety, and bipolar disorder, are common conditions that arise as a result of complex and heterogeneous combinations of genetic and environmental factors. In contrast to childhood neurodevelopmental conditions such as autism and intellectual disability, there are no clinical practice guidelines for applying genetic testing in the context of these conditions. But genetic counseling and genetic testing are not synonymous, and people who live with psychiatric disorders and their family members are often interested in what psychiatric genetic counseling can offer. Further, research shows that it can improve outcomes like empowerment for this population. Despite this, psychiatric genetic counseling is not yet routinely or widely offered. This review describes the state of the evidence about the process and outcomes of psychiatric genetic counseling, focusing on its clinical implications and remaining research gaps.
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页数：14
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