Two new protostane-type triterpenoids from Alisma orientalis

被引：22
作者：
Xin, Xiu-Lan [1 ,2 ]
Zhao, Xin-Yu [2 ,3 ]
Huo, Xiao-Kui [2 ]
Tian, Xiang-Ge [4 ]
Sun, Cheng-Peng [2 ]
Zhang, Hou-Li [2 ]
Tian, Yan [2 ]
Liu, Yong [3 ]
Wang, Xun [5 ]
机构：
[1] Beijing Polytech, Coll Bioengn, Beijing, Peoples R China
[2] Dalian Med Univ, Coll Pharm, Key Lab Metab & Transport Liaoning, Dalian, Peoples R China
[3] Chinese Med Univ, Clin Lab Shengjing Hosp, Shenyang, Peoples R China
[4] Dalian Med Univ, Basic Med Coll, Dalian, Peoples R China
[5] Dalian Med Univ, Nondirectly Affliated Hosp, Peoples Hosp Dalian 3, Dept Nuerosurg, Dalian, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2018年 / 32卷 / 02期
关键词：
Alisma orientalis; protostane-type triterpenoid; HCE-2; BIOLOGICAL-ACTIVE TRITERPENES; CARBOXYLESTERASE INHIBITORS; SUNFLOWER POLLEN; RHIZOME; SESQUITERPENES; DERIVATIVES; ACTIVATION; EXTRACT; ALISOLS;
D O I：
10.1080/14786419.2017.1344660
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new protostane-type triterpenoids, 17-epi alisolide (1) and 24-epi alismanol D (2), were isolated from Alisma orientalis together with one known compound. Their structural elucidations were conducted by NMR, UV and HRESIMS spectroscopic analyses, and comparison with the literature data. All the isolated compounds were evaluated for inhibitory effects on HCE-2. Compound 2 displayed moderate inhibitory activity against HCE-2 with IC50 value of 23.1M.
引用
收藏
页码：189 / 194
页数：6
相关论文
共 50 条
  • [21] A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis
    Jiang, Zhi-Yong
    Zhang, Xue-Mei
    Zhang, Feng-Xue
    Liu, Ni
    Zhao, Fang
    Zhou, Jun
    Chen, Ji-Jun
    PLANTA MEDICA, 2006, 72 (10) : 951 - 954
  • [22] Two new triterpenoids from Gypsophila oldhamiana
    Xie, Long-Xiao
    Zhang, Hao-Chao
    Wang, Hai-Yang
    Wang, Yan
    Wang, Feng-Ling
    Sun, Jing-Yong
    NATURAL PRODUCT RESEARCH, 2016, 30 (09) : 1068 - 1074
  • [23] Two new triterpenoids from the fungusDiplodia cupressi
    Liu, Xiao-Yu
    Wang, Xiao-Ling
    Shen, Tao
    Ren, Dong-Mei
    Lou, Hong-Xiang
    Wang, Xiao-Ning
    NATURAL PRODUCT RESEARCH, 2020, 34 (15) : 2179 - 2185
  • [24] Structure of orientanone from Alisma orientalis, a novel sesquiterpene originating from guaiane-type carbon skeleton by isopropyl shift
    Peng, GP
    Lou, FC
    Huang, XF
    Tian, G
    TETRAHEDRON, 2002, 58 (44) : 9045 - 9048
  • [25] Two new triterpenoids from the fungus Perenniporia maackiae
    Guo, Hua
    Si, Jing
    Li, Zheng-Hui
    Feng, Tao
    Dong, Ze-Jun
    Dai, Yu-Cheng
    Liu, Ji-Kai
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2013, 15 (03) : 253 - 257
  • [26] Two New Triterpenoids from the Roots of Rhodomyrtus tomentosa
    Zhang, Yu-Bo
    Li, Wen
    Zhang, Ze-Ming
    Chen, Neng-Hua
    Zhang, Xiang-Qiang
    Jiang, Jian-Wei
    Wang, Guo-Cai
    Li, Yao-Lan
    CHEMISTRY LETTERS, 2016, 45 (03) : 368 - 370
  • [27] Two New Diterpenoids from Thuja orientalis and Their Cytotoxicity
    Kim, Chung Sub
    Suh, Won Se
    Choi, Sang Un
    Kim, Ki Hyun
    Lee, Kang Ro
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (09) : 2855 - 2858
  • [28] A protostane and two lanostanes from the bark of Garcinia ferrea
    Bui, Danh A.
    Vu, Minh K.
    Nguyen, Hiep D.
    Nguyen, Le-Thu T.
    Dang, Son V.
    Nguyen, Lien-Hoa D.
    PHYTOCHEMISTRY LETTERS, 2014, 10 : 123 - 126
  • [29] Two new pentacyclic triterpenoids from the stems of Manihot esculenta
    Pan, Ya-Mei
    Zou, Tao
    Chen, Yong-Ju
    Chen, Jian-Yong
    Ding, Xiao
    Zhang, Yu
    Hao, Xiao-Jiang
    He, Hong-Ping
    PHYTOCHEMISTRY LETTERS, 2015, 12 : 273 - 276
  • [30] New Cucurbitane-Type Triterpenoids from Bryonia aspera
    Sahranavard, Shamim
    Naghibi, Farzaneh
    Siems, Karsten
    Jenett-Siems, Kristina
    PLANTA MEDICA, 2010, 76 (10) : 1014 - 1017
12345