Direct Benzylic Oxidation with Sodium Hypochlorite Using a New Efficient Catalytic System: TEMPO/Co(OAc)2

被引：45
作者：
Jin, Can [1 ]
Zhang, Li [1 ]
Su, Weike [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Minist Educ, Key Lab Pharmaceut Engn, Hangzhou 310014, Zhejiang, Peoples R China
来源：
SYNLETT | 2011年 / 10期
基金：
中国国家自然科学基金;
关键词：
benzylic oxidation; arenes; transition metals; TEMPO; sodium hypochlorite; SELECTIVE OXIDATION; SECONDARY ALCOHOLS; CARBONYL-COMPOUNDS; ORGANIC-COMPOUNDS; TEMPO; ACID; ALKYLAROMATICS; HYDROCARBONS; PORPHYRINS; ALDEHYDES;
D O I：
10.1055/s-0030-1260760
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct benzylic oxidation of arenes was achieved using NaClO/TEMPO/Co(OAc)(2). Various aromatic aldehydes and ketones were obtained from alkylarenes directly by benzylic oxidation in good to excellent yields. The reaction reactivity, selectivity, and scope of the reaction were investigated.
引用
收藏
页码：1435 / 1438
页数：4
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