[1] Sapienza Univ Rome, Dept Clin Internal Anesthesiol & Cardiovasc Sci, Rome, Italy
[2] Sapienza Rome, Dept Publ Hlth & Infect Dis, Rome, Italy
[3] San Luigi Gonzaga Univ Hosp, Orbassano, Italy
[4] Weill Cornell Med Coll, Clin Med & Populat Hlth Sci, New York, NY USA
[5] Univ Penn, Div Cardiovasc Med, Philadelphia, PA 19104 USA