Imaging host-pathogen interactions

被引：6

作者：

Campisi, Laura ^{[1
,2
]}

Brau, Frederic ^{[2
,3
]}

Glaichenhaus, Nicolas ^{[1
,2
]}

机构：

[1] CNRS, Inst Pharmacol Mol & Cellulaire, Inst Natl Sante Rech Med, U924, F-06560 Valbonne, France

[2] Univ Nice, UFR Sci, Nice, France

[3] CNRS, UMR6097, Valbone, France

来源：

IMMUNOLOGICAL REVIEWS | 2008年 / 221卷

关键词：

intravital microscopy; wide field epifluorescence microscopy; confocal laser scanning microcopy; spinning disk confocal microscopy; Salmonella; Plasmodium; REGULATORY T-CELLS; PLASMODIUM-BERGHEI SPOROZOITES; MALARIA PARASITES; DENDRITIC CELLS; REAL-TIME; IMMUNE-RESPONSES; LIVER STAGES; ACTIVATION; EXPRESSION; INFECTION;

D O I：

10.1111/j.1600-065X.2008.00586.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Imaging techniques have been revolutionized by advancements in both microscope instrumentation and data collection processing software. Immunologists and microbiologists now have access to a large panel of powerful technologies that are characterized by different spatial and time resolutions. In this review, we discuss recent studies in which emerging imaging technologies have been used to decipher the complexity of the interactions between pathogens and their mammalian hosts. By focusing on two very different pathogens, Plasmodium and Salmonella, we emphasize the critical role of imaging studies in the understanding of the host's immune system response to a pathogen.

引用

页码：188 / 199

页数：12

共 78 条

[1] Quantitative imaging of Plasmodium transmission from mosquito to mammal [J].

Amino, R ;

Thiberge, S ;

Martin, B ;

Celli, S ;

Shorte, S ;

Frischknecht, F ;

Ménard, R .

NATURE MEDICINE, 2006, 12 (02) :220-224

[2] Imaging malaria sporozoites in the dermis of the mammalian host [J].

Amino, Rogerio ;

Thiberge, Sabine ;

Blazquez, Samantha ;

Baldacci, Patricia ;

Renaud, Olivier ;

Shorte, Spencer ;

Menard, Robert .

NATURE PROTOCOLS, 2007, 2 (07) :1705-1712

[3] Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior [J].

Auffray, Cedric ;

Fogg, Darin ;

Garfa, Meriem ;

Elain, Gaelle ;

Join-Lambert, Olivier ;

Kayal, Samer ;

Sarnacki, Sabine ;

Cumano, Ana ;

Lauvau, Gregoire ;

Geissmann, Frederic .

SCIENCE, 2007, 317 (5838) :666-670

[4] Natural killer cell behavior in lymph nodes revealed by static and real-time imaging [J].

Bajénoff, M ;

Breart, B ;

Huang, AYC ;

Qi, H ;

Cazareth, J ;

Braud, VM ;

Germain, RN ;

Glaichenhaus, N .

JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (03) :619-631

[5] Immunobiology of dendritic cells [J].

Banchereau, J ;

Briere, F ;

Caux, C ;

Davoust, J ;

Lebecque, S ;

Liu, YT ;

Pulendran, B ;

Palucka, K .

ANNUAL REVIEW OF IMMUNOLOGY, 2000, 18 :767-+

[6] Natural regulatory T cells in infectious disease [J].

Belkaid, Y ;

Rouse, BT .

NATURE IMMUNOLOGY, 2005, 6 (04) :353-360

[7] CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity [J].

Belkaid, Y ;

Piccirillo, CA ;

Mendez, S ;

Shevach, EM ;

Sacks, DL .

NATURE, 2002, 420 (6915) :502-507

[8] In vivo visualization of bacterial colonization, antigen expression, and specific T-cell induction following oral administration of live recombinant Salmonella enterica serovar typhimurium [J].

Bumann, D .

INFECTION AND IMMUNITY, 2001, 69 (07) :4618-4626

[9] Stochastic monoallelic expression of IL-10 in T cells [J].

Calado, Dinis Pedro ;

Paixao, Tiago ;

Holmberg, Dan ;

Haury, Matthias .

JOURNAL OF IMMUNOLOGY, 2006, 177 (08) :5358-5364

[10] IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages [J].

Carvalho, LH ;

Sano, GI ;

Hafalla, JCR ;

Morrot, A ;

de Lafaille, MAC ;

Zavala, F .

NATURE MEDICINE, 2002, 8 (02) :166-170

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