Left temporoparietal transcranial magnetic stimulation in treatment-resistant schizophrenia with verbal hallucinations

被引:18
作者
Franck, N [1 ]
Poulet, E [1 ]
Terra, JL [1 ]
Daléry, J [1 ]
d'Amato, T [1 ]
机构
[1] Ctr Hosp Vinatier, F-69677 Bron, France
关键词
schizophrenia; repetitive transmagnetic stimulation; violence; Scale for the Assessment of Positive Symptoms;
D O I
10.1016/S0165-1781(03)00148-3
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Left temporoparietal repetitive transcranial magnetic stimulation (rTMS) reportedly diminishes verbal hallucinations. A 21-year-old schizophrenic man, who had killed his mother in the belief that she was a demon, failed to respond to combined treatment with a variety of antipsychotic agents. His persistent hallucinations consisted of two voices (God and the Devil). As an adjunct to continued antipsychotic medication, the patient received a course of rTMS: 10 sessions of 1-Hz stimulations near Wernicke's area. After rTMS, the patient's hallucinations grew less intrusive and he no longer required isolation. Although the improvement could be a delayed effect of medication, further trials of rTMS in cases of this type appear justified. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:107 / 109
页数:3
相关论文
共 6 条
[1]  
*AM PSYCH ASS, 1994, DSM, V4
[2]   Activation of Heschl's Gyrus during auditory hallucinations [J].
Dierks, T ;
Linden, DEJ ;
Jandl, M ;
Formisano, E ;
Goebel, R ;
Lanfermann, H ;
Singer, W .
NEURON, 1999, 22 (03) :615-621
[3]   Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices" [J].
Hoffman, RE ;
Boutros, NN ;
Berman, RM ;
Roessler, E ;
Belger, A ;
Krystal, JH ;
Charney, DS .
BIOLOGICAL PSYCHIATRY, 1999, 46 (01) :130-132
[4]   Transcranial magnetic stimulation and auditory hallucinations in schizophrenia [J].
Hoffman, RE ;
Boutros, NN ;
Hu, S ;
Berman, RM ;
Krystal, JH ;
Charney, DS .
LANCET, 2000, 355 (9209) :1073-1075
[5]   Neural network models of schizophrenia [J].
Hoffman, RE ;
McGlashan, TH .
NEUROSCIENTIST, 2001, 7 (05) :441-454
[6]   Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging [J].
Shergill, SS ;
Brammer, MJ ;
Williams, SCR ;
Murray, RM ;
McGuire, PK .
ARCHIVES OF GENERAL PSYCHIATRY, 2000, 57 (11) :1033-1038