Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4-10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures.
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Univ Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USAUniv Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USA
Sciaudone, Anthony
Corkrey, Heather
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Univ Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USAUniv Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USA
Corkrey, Heather
Humphries, Fiachra
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Univ Massachusetts, Chan Med Sch, Dept Med, Div Innate Immun, Worcester, MA USAUniv Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USA
Humphries, Fiachra
Koupenova, Milka
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Univ Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USA
Albert Sherman Ctr, UMass Chan Med Sch, 368 Plantat St, AS7-1041, Worcester, MA 01605 USAUniv Massachusetts, Chan Med Sch, Dept Med, Div Cardiovasc Med, Worcester, MA USA