Vaccine effectiveness against infection and onwards transmission of COVID-19: Analysis of Belgian contact tracing data, January-June 2021

被引：29
作者：
Braeye, Toon [1 ]
Cornelissen, Laura [1 ]
Catteau, Lucy [1 ]
Haarhuis, Freek [1 ]
Proesmans, Kristiaan [1 ]
De Ridder, Karin [1 ]
Djiena, Achille [2 ]
Mahieu, Romain [3 ]
De Leeuw, Frances [3 ]
Dreuw, Alex [4 ]
Hammami, Naima [5 ]
Quoilin, Sophie [1 ]
Van Oyen, Herman [1 ]
Wyndham-Thomas, Chloe [1 ]
Van Cauteren, Dieter [1 ]
机构：
[1] Sciensano, Dept Epidemiol & Publ Hlth, Brussels, Belgium
[2] Agence Vie Qualite, Charleroi, Belgium
[3] Common Community Commiss Brussels, Brussels, Belgium
[4] Minist German Speaking Community, Eupen, Belgium
[5] Agcy Care & Hlth Infect Prevent & Control, Flemish Community, Ghent, Belgium
来源：
VACCINE | 2021年 / 39卷 / 39期
关键词：
D O I：
10.1016/j.vaccine.2021.08.060
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In Belgium, high-risk contacts of an infected person were offered PCR-testing irrespective of their vacci-nation status. We estimated vaccine effectiveness (VE) against infection and onwards transmission, con-trolling for previous infections, household-exposure and temporal trends. We included 301,741 tests from 25 January to 24 June 2021. Full-schedule vaccination was associated with significant protection against infection. In addition, mRNA-vaccines reduced onward transmission: VE-estimates increased to >90% when index and contact were fully vaccinated. The small number of viral-vector vaccines included limited interpretability. (C) 2021 The Author(s). Published by Elsevier Ltd.
引用
收藏
页码：5456 / 5460
页数：5
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