EVALUATION OF IN VITRO ANTIOXIDANT POTENTIAL OF AQUEOUS EXTRACT OF TRAPA NATANS L. FRUITS

被引：1

作者：

Malviya, Neelesh ^{[1
]}

Jain, Sanjay ^{[1
]}

Jain, Avnish ^{[1
]}

Jain, Sourabh ^{[1
]}

Gurjar, Rajenda ^{[1
]}

机构：

[1] Smriti Coll Pharmaceut Educ, Dept Pharmacognosy, Indore 452010, Madhya Pradesh, India

来源：

ACTA POLONIAE PHARMACEUTICA | 2010年 / 67卷 / 04期

关键词：

Trapa natans L; aqueous extract; antioxidant activity; OXIDATIVE STRESS; TOXICITY; TEA; SUPEROXIDE; PROTEIN;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In the present study, the in vim, antioxidant potential of aqueous extract of Trapa unions L. fruits rind was investigated. The extract was found to contain a large amount of polyphenols and also exhibited an immense reducing ability. The total content of phenolic, flavonoid and tannin compounds was estimated as 63.81 mg of gallic acid equivalents/g of dry material. 21.34 mg of rutin equivalents/g of dry material and 17.11 mg of total tannin equivalent /g of dry material. respectively. IC(50) values for different antioxidant model were calculated as 128.86 mu g/mL for DPPH radicals, 97.65 mu g/mL for O(2)(center dot-) 148.32 mu g/mL for H(2)O(2) and 123.01 for NO. respectively. Reducing power and inhibition of center dot OH radical-induced BSA oxidation were also determined. The data obtained in the present study suggest that the aqueous extract of Trapa natans L. fruit rind have significant antioxidant activity against free radicals.

引用

页码：391 / 396

页数：6

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