Risk analysis for early mortality in emergency acute type A aortic dissection surgery: experience of Tokyo Acute Aortic Super-network

被引:18
|
作者
Yamasaki, Manabu [1 ,2 ]
Yoshino, Hideaki [1 ]
Kunihara, Takashi [1 ]
Akutsu, Koichi [1 ]
Shimokawa, Tomoki [1 ]
Ogino, Hitoshi [1 ]
Kawata, Mitsuhiro [1 ]
Takahashi, Toshiyuki [1 ]
Usui, Michio [1 ]
Watanabe, Kazuhiro [1 ]
Masuhara, Hiroshi [1 ]
Yamamoto, Takeshi [1 ]
Nagao, Ken [1 ]
Takayama, Morimasa [1 ]
机构
[1] Tokyo CCU Network Sci Comm, Tokyo, Japan
[2] St Lukes Int Hosp, Dept Cardiovasc Surg, Tokyo, Japan
关键词
Acute aortic dissection; Mortality; Malperfusion; Surgery; Network; INTERNATIONAL-REGISTRY; CLINICAL PRESENTATION; GERMAN REGISTRY; CARDIAC-SURGERY; OUTCOMES; MALPERFUSION; REPAIR; MANAGEMENT; TRENDS; IMPACT;
D O I
10.1093/ejcts/ezab146
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES: We investigated the various pre- and postoperative complications related to early (30-day) mortality after open surgery for acute type A aortic dissection. METHODS: Data from the Tokyo Acute Aortic Super-network database spanning January 2015 to December 2017 were retrospectively reviewed. Pre- and postoperative factors related to early postoperative mortality were assessed in 1504 of 2058 (73.0%) consecutive patients [age: 66.6 (SD: 13.5) years, male: 52.9%] who underwent acute type A aortic dissection repair. RESULTS: The early mortality rate following surgical repair was 8.9%. According to multivariable analysis, male sex [odds ratio (OR) 1.670, 95% confidence interval (CI) 1.063-2.624, P=0.026], use of percutaneous circulatory assist devices (n=116, 7.7%) including extracorporeal membrane oxygenators or intra-aortic balloon pumps (OR 4.857, 95% CI 2.867-8.228, P<0.001), shock (n=162, 10.8%) (OR 3.06, 95% CI 1.741-5.387, P<0.001), cardiopulmonary arrest (n=41, 2.7%) (OR 7.534, 95% CI 3.407-16.661, P<0.001), coronary ischaemia (n=36, 2.3%) (OR 2.583, 95% CI 1.042-6.404, P=0.041) and cerebral ischaemia (n=59, 3.9%) (OR 2.904, 95% CI 1.347-6.261, P=0.007) were independent preoperative risk factors for early mortality, while cardiac tamponade (n=34, 2.3%) (OR 10.282, 95% CI 4.640-22.785, P<0.001), cerebral ischaemia (n=80, 5.3%) (OR 2.409, 95% CI 1.179-4.923, P=0.016) and mesenteric ischaemia (n=15, 1.0%) (OR 44.763, 95% CI 13.027-153.808, P<0.001) were independent postoperative risk factors. CONCLUSIONS: Not only critical preoperative conditions but also postoperative cardiac tamponade and vital organ ischaemia are risk factors for early mortality after acute type A aortic dissection repair.
引用
收藏
页码:957 / 964
页数:8
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